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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for USP8 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006511 ubiquitin-dependent protein catabolic process IEA GO:0007032 endosome organization IMP GO:0007049 cell cycle IEA GO:0007265 Ras protein signal transduction IEA GO:0008283 cell proliferation TAS GO:0070536 protein K63-linked deubiquitination IDA GO:0071108 protein K48-linked deubiquitination IDA cellular_component GO:0005622 intracellular IEA GO:0005634 nucleus IEA GO:0005737 cytoplasm IEA GO:0005769 early endosome IDA GO:0005829 cytosol IDA GO:0005886 plasma membrane IEA GO:0019897 extrinsic to plasma membrane IDA GO:0031313 extrinsic to endosome membrane IEA molecular_function GO:0004197 cysteine-type endopeptidase activity TAS GO:0004221 ubiquitin thiolesterase activity IEA GO:0004843 ubiquitin-specific protease activity IDA GO:0005515 protein binding IPI GO:0008233 peptidase activity IEA GO:0008234 cysteine-type peptidase activity IEA GO:0017124 SH3 domain binding IEA

Protein-protein interaction details for USP8 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID YWHAB Affinity Capture-MS physical 17353931 YWHAZ Affinity Capture-MS physical 17353931 YWHAQ Affinity Capture-MS physical 17353931 SFN Affinity Capture-MS physical 15778465 RNF41 Affinity Capture-MS physical 15314180 RNF41 Affinity Capture-Western physical 15314180 OTUB1 Affinity Capture-Western physical 14661020 RNF128 Affinity Capture-Western physical 14661020 STAM2 Protein-peptide physical 13129930 STAM2 Reconstituted Complex physical 10982817 STAM2 Affinity Capture-Western physical 10982817 STAM Reconstituted Complex physical 10982817 STAM2 Reconstituted Complex physical 10982817 GRB2 Reconstituted Complex physical 10982817 KIF23 Affinity Capture-Western physical 18329369 BIRC6 Affinity Capture-Western physical 18329369 KRT31 Affinity Capture-MS physical 19615732 KRT85 Affinity Capture-MS physical 19615732 KRT36 Affinity Capture-MS physical 19615732 USP22 Affinity Capture-MS physical 19615732 RPL6P1 Affinity Capture-MS physical 19615732 AKT1 Affinity Capture-Western physical 17210635 UBC Affinity Capture-Western physical 16771824 EPS15 Affinity Capture-Western physical 16771824 EGFR Affinity Capture-Western physical 16120644 CHMP1B Two-hybrid physical 17711858 CHMP1B Reconstituted Complex physical 17711858 CHMP1A Reconstituted Complex physical 17711858 CHMP4C Reconstituted Complex physical 17711858 CHMP7 Reconstituted Complex physical 17711858 CHMP1B Affinity Capture-Western physical 17711858 STAM Biochemical Activity physical 17711858 KCNN4 Affinity Capture-Western physical 21828287 YWHAQ Affinity Capture-MS physical 15161933 YWHAB Affinity Capture-MS physical 15324660 YWHAG Affinity Capture-MS physical 15324660 YWHAZ Affinity Capture-MS physical 15324660 YWHAQ Affinity Capture-MS physical 15324660 STAM Affinity Capture-Western physical 20736164 STAM PCA physical 20736164 STAM2 PCA physical 20736164 PLA2G2A Biochemical Activity physical 22118674 UBC Affinity Capture-MS physical 22118674 STAM Affinity Capture-Western physical 16520378