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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HGS (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006886 intracellular protein transport IEA GO:0007165 signal transduction TAS GO:0007173 epidermal growth factor receptor signaling pathway TAS GO:0008285 negative regulation of cell proliferation TAS GO:0016044 cellular membrane organization TAS GO:0016197 endosome transport NAS GO:0016197 endosome transport TAS GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway TAS GO:0042176 regulation of protein catabolic process TAS GO:0046426 negative regulation of JAK-STAT cascade IDA cellular_component GO:0005737 cytoplasm IDA GO:0005768 endosome IDA GO:0005769 early endosome IDA GO:0005829 cytosol TAS GO:0016020 membrane IEA GO:0031901 early endosome membrane IEA GO:0032585 multivesicular body membrane IEA GO:0043231 intracellular membrane-bounded organelle IDA molecular_function GO:0005515 protein binding IPI GO:0019904 protein domain specific binding IPI GO:0046872 metal ion binding IEA

Protein-protein interaction details for HGS (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CLTC Two-hybrid physical 11532964 HAP1 Two-hybrid physical 12021262 VPS37C Two-hybrid physical 15509564 EXOC7 Two-hybrid physical 16189514 KRT19 Two-hybrid physical 16189514 GKAP1 Two-hybrid physical 16189514 USHBP1 Two-hybrid physical 16189514 EHMT2 Two-hybrid physical 16189514 EXOC8 Two-hybrid physical 16189514 NMI Two-hybrid physical 16189514 MIF4GD Two-hybrid physical 16189514 LDOC1 Two-hybrid physical 16189514 CCDC33 Two-hybrid physical 16189514 BEGAIN Two-hybrid physical 16189514 C1orf190 Two-hybrid physical 16189514 DAZAP2 Two-hybrid physical 16189514 UBE2I Two-hybrid physical 16189514 STAM2 Two-hybrid physical 16189514 MED7 Two-hybrid physical 16189514 KRT18 Two-hybrid physical 16189514 UBQLN1 Two-hybrid physical 16189514 TADA2A Two-hybrid physical 16189514 STAM Two-hybrid physical 16189514 TSG101 Two-hybrid physical 16189514 TSG101 Two-hybrid physical 12802020 TSG101 Affinity Capture-Western physical 12802020 TSG101 Affinity Capture-Western physical 12802020 NF2 Reconstituted Complex physical 11285248 DLG4 Two-hybrid physical 12151521 DLG4 Affinity Capture-Western physical 12151521 EPS15 Reconstituted Complex physical 10809762 EPS15 Two-hybrid physical 10809762 STAM Affinity Capture-Western physical 9407053 HAP1 Reconstituted Complex physical 12021262 HAP1 Affinity Capture-Western physical 12021262 STAM Co-fractionation physical 12551915 STAM2 Co-fractionation physical 12551915 EPS15 Co-fractionation physical 12551915 STAM2 Affinity Capture-Western physical 12551915 SNX1 Reconstituted Complex physical 11110793 PAK1 Reconstituted Complex physical 11397816 MAP3K7 Reconstituted Complex physical 11397816 NF2 Two-hybrid physical 10861283 NF2 Affinity Capture-Western physical 10861283 NF2 Affinity Capture-Western physical 10861283 NF2 Reconstituted Complex physical 10861283 LYST Two-hybrid physical 11984006 LYST Reconstituted Complex physical 11984006 NEDD4 Biochemical Activity physical 12230472 SCAMP3 Affinity Capture-Western physical 19158374 APP Reconstituted Complex physical 19019082 APLP2 Reconstituted Complex physical 19019082 ATP2A2 Reconstituted Complex physical 19019082 ARL6IP1 Reconstituted Complex physical 19019082 BSG Reconstituted Complex physical 19019082 C3orf1 Reconstituted Complex physical 19019082 FAM5C Reconstituted Complex physical 19019082 TMEM49 Reconstituted Complex physical 19019082 SUN2 Reconstituted Complex physical 19019082 AHCYL1 Reconstituted Complex physical 19019082 CASK Reconstituted Complex physical 19019082 TJP2 Reconstituted Complex physical 19019082 HSPA8 Reconstituted Complex physical 19019082 MAP3K10 Reconstituted Complex physical 19019082 STXBP1 Reconstituted Complex physical 19019082 SCRN1 Reconstituted Complex physical 19019082 CRMP1 Reconstituted Complex physical 19019082 DCTN2 Reconstituted Complex physical 19019082 GFAP Reconstituted Complex physical 19019082 MARK4 Reconstituted Complex physical 19019082 PPP1R16A Reconstituted Complex physical 19019082 RHOBTB3 Reconstituted Complex physical 19019082 TUBB2A Reconstituted Complex physical 19019082 ESRRG Reconstituted Complex physical 19019082 ILKAP Reconstituted Complex physical 19019082 PPP1R7 Reconstituted Complex physical 19019082 RSU1 Reconstituted Complex physical 19019082 UBA1 Reconstituted Complex physical 19019082 ACLY Reconstituted Complex physical 19019082 CBS Reconstituted Complex physical 19019082 DECR1 Reconstituted Complex physical 19019082 MAT2A Reconstituted Complex physical 19019082 MTHFD1L Reconstituted Complex physical 19019082 OSBPL5 Reconstituted Complex physical 19019082 PLD3 Reconstituted Complex physical 19019082 PFKM Reconstituted Complex physical 19019082 HNRPDL Reconstituted Complex physical 19019082 RPS3A Reconstituted Complex physical 19019082 SF3B3 Reconstituted Complex physical 19019082 NCRNA00265 Reconstituted Complex physical 19019082 PTCD3 Reconstituted Complex physical 19019082 ZNF302 Reconstituted Complex physical 19019082 MEST Reconstituted Complex physical 19019082 TMCC2 Reconstituted Complex physical 19019082 ATP1A1 Reconstituted Complex physical 19019082 TRAP1 Reconstituted Complex physical 19019082 GGA2 Reconstituted Complex physical 19019082 TUBB Reconstituted Complex physical 19019082 CLTC Reconstituted Complex physical 11532964 IL2RB Affinity Capture-Western physical 18445679 IL2RB Reconstituted Complex physical 18445679 EGFR Affinity Capture-Western physical 18508924 UBC Affinity Capture-Western physical 17101784 UBC Affinity Capture-Western physical 16771824 UBC Affinity Capture-Western physical 16735510 NEDD8 Affinity Capture-Western physical 16735510 UBC Affinity Capture-Western physical 16735510 NEDD8 Affinity Capture-Western physical 16735510 CLTC Affinity Capture-Western physical 16716190 APC Two-hybrid physical 20936779 VPS4A Affinity Capture-Western physical 14602072 UBC Affinity Capture-Western physical 14602072 ITCH Affinity Capture-Western physical 14602072 OCLN Affinity Capture-Western physical 19478092 GJA1 Co-localization physical 19808888 ABCA1 Affinity Capture-Western physical 21520210 JAG1 Affinity Capture-Western physical 20720151 SH3KBP1 Affinity Capture-Western physical 21635887 ARRB1 Affinity Capture-Western physical 20505072 ARR3 Affinity Capture-Western physical 20505072 STAM Reconstituted Complex physical 20505072 UBC Affinity Capture-Western physical 20505072 TSG101 Two-hybrid physical 17229889 IL4R Affinity Capture-Western physical 21362618 IL2RB Affinity Capture-Western physical 21362618 IL4R Reconstituted Complex physical 21362618 IL2RB Reconstituted Complex physical 21362618 SCNN1A Affinity Capture-Western physical 20675381 SCNN1A Affinity Capture-Western physical 20675381 NEDD4 Affinity Capture-Western physical 20675381 UBC Affinity Capture-Western physical 20675381 UBC Affinity Capture-MS physical 21987572