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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for AURKB (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000087 M phase of mitotic cell cycle TAS GO:0000236 mitotic prometaphase TAS GO:0000278 mitotic cell cycle TAS GO:0000910 cytokinesis IEA GO:0007049 cell cycle IEA GO:0007568 aging IEA GO:0008283 cell proliferation IEA GO:0008608 attachment of spindle microtubules to kinetochore TAS GO:0016570 histone modification TAS GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process TAS GO:0034501 protein localization to kinetochore IMP GO:0046777 protein autophosphorylation TAS GO:0051256 spindle midzone assembly involved in mitosis IMP GO:0051256 spindle midzone assembly involved in mitosis TAS GO:0051983 regulation of chromosome segregation TAS GO:0071777 positive regulation of cell cycle cytokinesis IMP GO:0071777 positive regulation of cell cycle cytokinesis TAS cellular_component GO:0000779 condensed chromosome, centromeric region IDA GO:0000780 condensed nuclear chromosome, centromeric region IDA GO:0005634 nucleus IEA GO:0005694 chromosome IEA GO:0005737 cytoplasm IEA GO:0005819 spindle IEA GO:0005819 spindle TAS GO:0005829 cytosol TAS GO:0005856 cytoskeleton IEA GO:0030496 midbody IEA GO:0030496 midbody TAS GO:0032133 chromosome passenger complex IPI GO:0032133 chromosome passenger complex TAS molecular_function GO:0000166 nucleotide binding IEA GO:0004674 protein serine/threonine kinase activity IEA GO:0004712 protein serine/threonine/tyrosine kinase activity TAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for AURKB (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BIRC5 Two-hybrid physical 11516652 CDCA8 Affinity Capture-Western physical 15260989 CDCA8 Affinity Capture-Western physical 15249581 RCC2 Affinity Capture-Western physical 15249581 AURKB Affinity Capture-Western physical 15249581 INCENP Affinity Capture-Western physical 15249581 CDCA8 Biochemical Activity physical 15249581 TACC1 Affinity Capture-Western physical 15064709 TACC1 Affinity Capture-Western physical 15064709 RACGAP1 Biochemical Activity physical 12689593 BIRC5 Reconstituted Complex physical 12419797 BIRC5 Phenotypic Enhancement genetic 12419797 BIRC5 Reconstituted Complex physical 11516652 SGOL1 Affinity Capture-Western physical 17322402 BARD1 Affinity Capture-Western physical 19176389 BARD1 Affinity Capture-Western physical 19176389 BRCA2 Affinity Capture-Western physical 19176389 KIF20A Reconstituted Complex physical 15263015 RB1 Reconstituted Complex physical 19225156 RB1 Biochemical Activity physical 19225156 RB1 Affinity Capture-Western physical 19225156 INCENP Affinity Capture-Western physical 19951914 INCENP Co-localization physical 19951914 BIRC5 Co-localization physical 19951914 CDCA8 Co-localization physical 19951914 NSUN2 Biochemical Activity physical 17215513 CDCA8 Two-hybrid physical 18946085 INCENP Affinity Capture-Western physical 18773538 EVI5 Affinity Capture-Western physical 16764853 EVI5 Reconstituted Complex physical 16764853 INCENP Reconstituted Complex physical 11050385 HIST1H3A Reconstituted Complex physical 21397507 HIST1H3A Biochemical Activity physical 21397507 NOC2L Affinity Capture-Western physical 20959462 TP53 Affinity Capture-Western physical 20959462 RASSF1 Biochemical Activity physical 21874044 RASSF1 Biochemical Activity physical 21874044 BIRC5 Affinity Capture-Western physical 19995937 INCENP Affinity Capture-Western physical 19995937 KLHL9 Affinity Capture-Western physical 19995937 KLHL21 Affinity Capture-Western physical 19995937 KLHL9 Reconstituted Complex physical 19995937 KLHL21 Reconstituted Complex physical 19995937 KLHL21 Biochemical Activity physical 19995937 KLHL9 Biochemical Activity physical 19995937 KLHL13 Biochemical Activity physical 19995937 UBC Reconstituted Complex physical 19995937 UBC Affinity Capture-Western physical 20856855 INCENP Affinity Capture-Western physical 16239925 BIRC5 Affinity Capture-Western physical 17099693 CDCA8 Affinity Capture-Western physical 17099693 BIRC5 Reconstituted Complex physical 17099693 NCAPH Biochemical Activity physical 21633354 UBC Affinity Capture-MS physical 20639865 INCENP Reconstituted Complex physical 12925766 SUMO1 Affinity Capture-Western physical 20663916 SUMO2 Affinity Capture-Western physical 20663916 SUMO3 Affinity Capture-Western physical 20663916 SUMO2 Affinity Capture-Western physical 20663916 SUMO2 Reconstituted Complex physical 20663916 CENPA Biochemical Activity physical 20663916 HIST3H3 Biochemical Activity physical 20663916 UBC Affinity Capture-MS physical 21987572 SUMO1 Reconstituted Complex physical 21554500 SUMO1 Affinity Capture-Western physical 21554500 SUMO2 Affinity Capture-Western physical 21554500 HIST3H3 Biochemical Activity physical 21554500 INCENP Reconstituted Complex physical 21554500 CDCA8 Reconstituted Complex physical 21554500 BIRC5 Reconstituted Complex physical 21554500