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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SLC9A3R1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0003096 renal sodium ion transport IEA GO:0006461 protein complex assembly TAS GO:0006915 apoptosis IDA GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway IEA GO:0008285 negative regulation of cell proliferation IDA GO:0008285 negative regulation of cell proliferation IMP GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway ISS GO:0010766 negative regulation of sodium ion transport IEA GO:0014067 negative regulation of phosphatidylinositol 3-kinase cascade ISS GO:0016055 Wnt receptor signaling pathway IEA GO:0019933 cAMP-mediated signaling IEA GO:0030033 microvillus assembly IMP GO:0030036 actin cytoskeleton organization IEA GO:0030336 negative regulation of cell migration IEA GO:0030643 cellular phosphate ion homeostasis IEA GO:0032415 regulation of sodium:hydrogen antiporter activity NAS GO:0032416 negative regulation of sodium:hydrogen antiporter activity IEA GO:0032782 bile acid secretion ISS GO:0034613 cellular protein localization IEA GO:0034635 glutathione transport ISS GO:0044062 regulation of excretion IEA GO:0045859 regulation of protein kinase activity ISS GO:0051898 negative regulation of protein kinase B signaling cascade IMP GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway IEA GO:0070293 renal absorption ISS GO:0070373 negative regulation of ERK1 and ERK2 cascade IDA cellular_component GO:0001726 ruffle IEA GO:0005634 nucleus IDA GO:0005737 cytoplasm IDA GO:0005813 centrosome IDA GO:0005886 plasma membrane IDA GO:0005902 microvillus IDA GO:0012505 endomembrane system IEA GO:0015629 actin cytoskeleton TAS GO:0016020 membrane IDA GO:0016324 apical plasma membrane IEA GO:0030175 filopodium IEA GO:0031526 brush border membrane IEA GO:0031528 microvillus membrane ISS GO:0043231 intracellular membrane-bounded organelle IDA GO:0071944 cell periphery IDA molecular_function GO:0005102 receptor binding IPI GO:0005515 protein binding IPI GO:0008013 beta-catenin binding IPI GO:0017081 chloride channel regulator activity IDA GO:0019902 phosphatase binding IPI GO:0030165 PDZ domain binding IPI GO:0031698 beta-2 adrenergic receptor binding IPI GO:0043621 protein self-association IDA GO:0050780 dopamine receptor binding IEA GO:0070851 growth factor receptor binding IPI

Protein-protein interaction details for SLC9A3R1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID KCNJ1 Two-hybrid physical 14604981 OPRK1 Reconstituted Complex physical 15070904 OPRK1 Affinity Capture-Western physical 15070904 SLC9A3R1 Reconstituted Complex physical 15070904 KCNJ1 Reconstituted Complex physical 14604981 SLC9A3 Affinity Capture-Western physical 14580213 PDZK1 Two-hybrid physical 14531806 PDZK1 Reconstituted Complex physical 14531806 PIK3CA Reconstituted Complex physical 12954600 CTNNB1 Affinity Capture-Western physical 12830000 CTNNB1 Reconstituted Complex physical 12830000 ABCC2 Reconstituted Complex physical 12615054 CFTR Reconstituted Complex physical 12615054 CFTR Reconstituted Complex physical 9613608 CFTR Affinity Capture-Western physical 9613608 PLCB1 Affinity Capture-Western physical 10980202 YAP1 Reconstituted Complex physical 10562288 YAP1 Affinity Capture-Western physical 10562288 YES1 Reconstituted Complex physical 10562288 ADRB2 Co-crystal Structure physical 11882663 GNB2L1 Affinity Capture-Western physical 11956211 OPRK1 Affinity Capture-Western physical 12004055 SLC4A8 Reconstituted Complex physical 12444018 NOS2 Reconstituted Complex physical 12080081 GNAQ Affinity Capture-Western physical 12193606 GNAQ Reconstituted Complex physical 12193606 MSN Reconstituted Complex physical 9430655 NF2 Reconstituted Complex physical 9430655 TBC1D10A Reconstituted Complex physical 11285285 CFTR Affinity Capture-Western physical 10852925 CLCN3 Reconstituted Complex physical 12471024 CFTR Reconstituted Complex physical 12471024 PTH1R Far Western physical 12075354 PTH1R Affinity Capture-Western physical 12075354 PDGFRA Far Western physical 11046132 PDGFRB Far Western physical 11046132 PDGFRA Far Western physical 11046132 PDGFRB Far Western physical 11046132 PDGFRA Reconstituted Complex physical 11046132 PDGFRB Reconstituted Complex physical 11046132 PDGFRA Affinity Capture-Western physical 11046132 PDGFRB Affinity Capture-Western physical 11046132 SLC9A3R1 Far Western physical 11046132 ADRB2 Reconstituted Complex physical 9671706 P2RY1 Reconstituted Complex physical 9671706 CFTR Reconstituted Complex physical 9671706 ADRB2 Reconstituted Complex physical 9560162 PAG1 Two-hybrid physical 11684085 PAG1 Affinity Capture-Western physical 11684085 PAG1 Far Western physical 11684085 PAG1 Affinity Capture-Western physical 11684085 EZR Reconstituted Complex physical 11684085 PAG1 Co-fractionation physical 11684085 EZR Affinity Capture-Western physical 9314537 CFTR Reconstituted Complex physical 9677412 CFTR Protein-peptide physical 9677412 CFTR Protein-peptide physical 9677412 SCN4A Protein-peptide physical 9677412 CFTR Affinity Capture-Western physical 12403779 CFTR Reconstituted Complex physical 12403779 SLC4A8 Reconstituted Complex physical 12403779 PHLPP2 Affinity Capture-MS physical 19615732 MME Affinity Capture-MS physical 17342744 UBC Affinity Capture-MS physical 21987572