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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ACVRL1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001525angiogenesisIMP
GO:0001701in utero embryonic developmentIEA
GO:0001936regulation of endothelial cell proliferationTAS
GO:0001937negative regulation of endothelial cell proliferationIEA
GO:0001938positive regulation of endothelial cell proliferationIEA
GO:0001955blood vessel maturationTAS
GO:0002043blood vessel endothelial cell proliferation involved in sprouting angiogenesisTAS
GO:0006275regulation of DNA replicationTAS
GO:0006355regulation of transcription, DNA-dependentIMP
GO:0006468protein phosphorylationIDA
GO:0007162negative regulation of cell adhesionIMP
GO:0007165signal transductionIDA
GO:0007179transforming growth factor beta receptor signaling pathwayIDA
GO:0008015blood circulationIMP
GO:0008217regulation of blood pressureIMP
GO:0008285negative regulation of cell proliferationIMP
GO:0010596negative regulation of endothelial cell migrationIDA
GO:0030308negative regulation of cell growthIDA
GO:0030336negative regulation of cell migrationIMP
GO:0030513positive regulation of BMP signaling pathwayIDA
GO:0035313wound healing, spreading of epidermal cellsIMP
GO:0043535regulation of blood vessel endothelial cell migrationTAS
GO:0045602negative regulation of endothelial cell differentiationIEA
GO:0045603positive regulation of endothelial cell differentiationIEA
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0051291protein heterooligomerizationIEA
GO:0051895negative regulation of focal adhesion assemblyIMP
cellular_component
GO:0005887integral to plasma membraneIDA
GO:0009986cell surfaceIDA
GO:0016020membraneIEA
GO:0030425dendriteIEA
GO:0043025neuronal cell bodyIEA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0004672protein kinase activityIEA
GO:0004674protein serine/threonine kinase activityIDA
GO:0004674protein serine/threonine kinase activityIEA
GO:0004675transmembrane receptor protein serine/threonine kinase activityRCA
GO:0004702receptor signaling protein serine/threonine kinase activityIEA
GO:0004872receptor activityIEA
GO:0005024transforming growth factor beta-activated receptor activityIDA
GO:0005024transforming growth factor beta-activated receptor activityIEA
GO:0005025transforming growth factor beta receptor activity, type IIDA
GO:0005515protein bindingIPI
GO:0005524ATP bindingIDA
GO:0005524ATP bindingIEA
GO:0016361activin receptor activity, type IIDA
GO:0016361activin receptor activity, type ITAS
GO:0016772transferase activity, transferring phosphorus-containing groupsIEA
GO:0046332SMAD bindingIDA
GO:0046872metal ion bindingIEA
GO:0048185activin bindingIDA
GO:0050431transforming growth factor beta bindingIPI

Protein-protein interaction details for ACVRL1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
TGFB1Affinity Capture-Westernphysical10716993
SNX6Affinity Capture-Westernphysical11279102
TSC22D1Affinity Capture-Westernphysical21791611