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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CD80 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0007267cell-cell signalingIC
GO:0009967positive regulation of signal transductionNAS
GO:0031295T cell costimulationTAS
GO:0035556intracellular signal transductionNAS
GO:0042110T cell activationIC
GO:0044419interspecies interaction between organismsIEA
GO:0045086positive regulation of interleukin-2 biosynthetic processNAS
GO:0045425positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic processNAS
GO:0045627positive regulation of T-helper 1 cell differentiationNAS
GO:0045893positive regulation of transcription, DNA-dependentNAS
GO:0046641positive regulation of alpha-beta T cell proliferationIEA
GO:0050731positive regulation of peptidyl-tyrosine phosphorylationIDA
cellular_component
GO:0005622intracellularNAS
GO:0005886plasma membraneTAS
GO:0009897external side of plasma membraneIEA
GO:0016020membraneIEA
GO:0016021integral to membraneIC
GO:0016021integral to membraneIEA
molecular_function
GO:0004872receptor activityIEA
GO:0005515protein bindingIPI
GO:0015026coreceptor activityNAS

Protein-protein interaction details for CD80 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
CTLA4Reconstituted Complexphysical7545666
CD28Reconstituted Complexphysical7545666
CD80Co-crystal Structurephysical11279502
CTLA4Co-crystal Structurephysical11279502