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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MED21 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001824 blastocyst development IEA GO:0006351 transcription, DNA-dependent TAS GO:0006357 regulation of transcription from RNA polymerase II promoter TAS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA cellular_component GO:0005634 nucleus IEA GO:0016592 mediator complex IDA molecular_function GO:0003713 transcription coactivator activity IDA GO:0003899 DNA-directed RNA polymerase activity TAS

Protein-protein interaction details for MED21 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID POLR2A Affinity Capture-Western physical 9159119 POLR2A Co-purification physical 9159119 BRCA1 Co-purification physical 9159119 BRCA1 Affinity Capture-Western physical 9159119 GTF2E1 Affinity Capture-Western physical 9159119 GTF2E1 Co-purification physical 9159119 GTF2F1 Affinity Capture-Western physical 9159119 GTF2F1 Co-purification physical 9159119 GTF2H4 Affinity Capture-Western physical 9159119 GTF2H4 Co-purification physical 9159119 MED10 Affinity Capture-MS physical 15175163 MED9 Affinity Capture-MS physical 15175163 MED29 Affinity Capture-MS physical 15175163 MED19 Affinity Capture-MS physical 15175163 MED28 Affinity Capture-MS physical 15175163 MED26 Affinity Capture-MS physical 15175163 PPARGC1A Affinity Capture-Western physical 14636573 POLR2A Co-fractionation physical 9710619 CREBBP Affinity Capture-Western physical 9710619 POLR2A Affinity Capture-Western physical 9710619 KAT2B Affinity Capture-Western physical 9710619 SMARCB1 Affinity Capture-Western physical 9710619 CDK8 Co-fractionation physical 9710619 MED30 Reconstituted Complex physical 12584197 MED6 Co-purification physical 9734358 MED14 Co-purification physical 9734358 MED6 Co-purification physical 9734358 POLR2A Affinity Capture-Western physical 9315662 GTF2B Affinity Capture-Western physical 9315662 GTF2F1 Affinity Capture-Western physical 9315662 CDK7 Affinity Capture-Western physical 9315662 CDK8 Affinity Capture-Western physical 9315662 TCERG1 Affinity Capture-Western physical 9315662 CDK8 Affinity Capture-MS physical 10198638 THRA Affinity Capture-Western physical 10198638 VDR Affinity Capture-MS physical 10198638 HNF4A Reconstituted Complex physical 12101254 ESR2 Reconstituted Complex physical 11867769 ESR1 Reconstituted Complex physical 11867769 CDK8 Affinity Capture-Western physical 11867769 MED28 Reconstituted Complex physical 15989967 MED29 Reconstituted Complex physical 15989967 MED18 Reconstituted Complex physical 15989967 MED1 Affinity Capture-Western physical 15989967 MED30 Affinity Capture-Western physical 15989967 TRIM27 Two-hybrid physical 20211142 TARBP2 Two-hybrid physical 20211142 PCBD2 Two-hybrid physical 20211142 ZSCAN1 Two-hybrid physical 20211142 MED12 Affinity Capture-MS physical 20133760 MED18 Affinity Capture-MS physical 20133760 ZC3H13 Affinity Capture-MS physical 20133760 MED28 Affinity Capture-MS physical 20133760 SREBF1 Affinity Capture-MS physical 11834832 CDK8 Co-purification physical 10024883 TP53 Reconstituted Complex physical 10024883 MED10 Affinity Capture-Western physical 10882111 CDK8 Affinity Capture-Western physical 10882111 THRA Two-hybrid physical 15249124 THRA Reconstituted Complex physical 15249124 THRB Reconstituted Complex physical 15249124 UBC Affinity Capture-MS physical 21987572