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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for HAND2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001525 angiogenesis IEA GO:0001701 in utero embryonic development IEA GO:0001701 in utero embryonic development ISS GO:0001947 heart looping IEA GO:0001947 heart looping ISS GO:0003007 heart morphogenesis IEA GO:0003007 heart morphogenesis ISS GO:0003219 cardiac right ventricle formation IEA GO:0003266 regulation of secondary heart field cardioblast proliferation IEA GO:0003266 regulation of secondary heart field cardioblast proliferation ISS GO:0003357 noradrenergic neuron differentiation NAS GO:0006355 regulation of transcription, DNA-dependent IEA GO:0006355 regulation of transcription, DNA-dependent ISS GO:0006915 apoptosis IEA GO:0006915 apoptosis ISS GO:0007275 multicellular organismal development IEA GO:0007507 heart development NAS GO:0007512 adult heart development IEA GO:0007512 adult heart development IEP GO:0010667 negative regulation of cardiac muscle cell apoptosis IEA GO:0010667 negative regulation of cardiac muscle cell apoptosis ISS GO:0014032 neural crest cell development IEA GO:0014032 neural crest cell development ISS GO:0030154 cell differentiation IEA GO:0045893 positive regulation of transcription, DNA-dependent ISS GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0048538 thymus development IEA GO:0048538 thymus development ISS GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis IEA GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis ISS GO:2000679 positive regulation of transcription regulatory region DNA binding IDA cellular_component GO:0000790 nuclear chromatin IDA GO:0005634 nucleus IEA GO:0005667 transcription factor complex IEA GO:0005667 transcription factor complex ISS GO:0043234 protein complex IDA molecular_function GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IDA GO:0003677 DNA binding IEA GO:0003680 AT DNA binding IDA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003713 transcription coactivator activity ISS GO:0005515 protein binding IPI GO:0008134 transcription factor binding ISS GO:0019904 protein domain specific binding IEA GO:0033613 activating transcription factor binding IEA GO:0033613 activating transcription factor binding ISS GO:0042803 protein homodimerization activity IEA GO:0042803 protein homodimerization activity ISS GO:0044212 transcription regulatory region DNA binding ISS GO:0046982 protein heterodimerization activity IEA GO:0070888 E-box binding IDA GO:0070888 E-box binding IEA GO:0070888 E-box binding ISS

Protein-protein interaction details for HAND2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CENPB Two-hybrid physical 11812799 TCF3 Two-hybrid physical 11812799 PPP2R5D Two-hybrid physical 14636580 COPS5 Two-hybrid physical 11812799 PPP2R5D Reconstituted Complex physical 14636580 PRKCA Biochemical Activity physical 14636580 PRKACA Biochemical Activity physical 14636580 PHOX2A Reconstituted Complex physical 14506227 PHOX2A Affinity Capture-Western physical 14506227 GATA4 Reconstituted Complex physical 11994297 GATA4 Affinity Capture-Western physical 11994297 EP300 Reconstituted Complex physical 11994297 NPM1 Two-hybrid physical 11812799 HAND2 Reconstituted Complex physical 11812799 HOXD13 Affinity Capture-Western physical 20386744 HOXD13 Affinity Capture-Western physical 20386744