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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ROCK2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000910cytokinesisIEA
GO:0006468protein phosphorylationIDA
GO:0006468protein phosphorylationIEA
GO:0006939smooth muscle contractionTAS
GO:0007411axon guidanceTAS
GO:0010825positive regulation of centrosome duplicationIEA
GO:0016525negative regulation of angiogenesisIMP
GO:0030155regulation of cell adhesionTAS
GO:0032956regulation of actin cytoskeleton organizationTAS
GO:0035556intracellular signal transductionIEA
GO:0045616regulation of keratinocyte differentiationIMP
GO:0051298centrosome duplicationIMP
GO:0051492regulation of stress fiber assemblyTAS
GO:0051893regulation of focal adhesion assemblyTAS
GO:2000114regulation of establishment of cell polarityTAS
GO:2000145regulation of cell motilityTAS
cellular_component
GO:0005634nucleusIEA
GO:0005737cytoplasmIEA
GO:0005813centrosomeIDA
GO:0005829cytosolTAS
GO:0005856cytoskeletonIEA
GO:0005886plasma membraneIEA
GO:0031616spindle pole centrosomeIEA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0004674protein serine/threonine kinase activityIDA
GO:0004674protein serine/threonine kinase activityIEA
GO:0005198structural molecule activityNAS
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0016772transferase activity, transferring phosphorus-containing groupsIEA
GO:0046872metal ion bindingIEA

Protein-protein interaction details for ROCK2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
IKBKEAffinity Capture-MSphysical17353931
STK16Affinity Capture-MSphysical17353931
RHOAAffinity Capture-Westernphysical11350930