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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CD40 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002768immune response-regulating cell surface receptor signaling pathwayIEA
GO:0006461protein complex assemblyTAS
GO:0006954inflammatory responseTAS
GO:0007165signal transductionTAS
GO:0030168platelet activationNAS
GO:0030890positive regulation of B cell proliferationIEA
GO:0032735positive regulation of interleukin-12 productionIEA
GO:0042100B cell proliferationNAS
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIEP
GO:0048304positive regulation of isotype switching to IgG isotypesIEA
GO:0050776regulation of immune responseTAS
GO:0051023regulation of immunoglobulin secretionIEA
GO:0051607defense response to virusIEA
GO:0071260cellular response to mechanical stimulusIEP
GO:2000353positive regulation of endothelial cell apoptosisIDA
cellular_component
GO:0005576extracellular regionIEA
GO:0005886plasma membraneISS
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneTAS
GO:0009897external side of plasma membraneIEA
GO:0035631CD40 receptor complexISS
GO:0043231intracellular membrane-bounded organelleIEA
molecular_function
GO:0004871signal transducer activityTAS
GO:0004872receptor activityIEA
GO:0005515protein bindingIPI
GO:0019899enzyme bindingIPI

Protein-protein interaction details for CD40 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
UGGT1Affinity Capture-MSphysical17353931
CALRAffinity Capture-MSphysical17353931
SGK1Affinity Capture-MSphysical17353931
USP15Affinity Capture-MSphysical17353931
RFC5Affinity Capture-MSphysical17353931
ERP44Affinity Capture-MSphysical17353931
POLR2HAffinity Capture-MSphysical17353931
SLC30A7Affinity Capture-MSphysical17353931
TXNAffinity Capture-MSphysical17353931
DDX3XAffinity Capture-MSphysical17353931
RNF219Affinity Capture-MSphysical17353931
SLC39A7Affinity Capture-MSphysical17353931
FBLAffinity Capture-MSphysical17353931
NCOA6Reconstituted Complexphysical10847592
RIPK2Affinity Capture-Westernphysical9642260
TRAF2Co-crystal Structurephysical10411888
TRAF3Reconstituted Complexphysical9990007
TRAF5Reconstituted Complexphysical9990007
TRAF6Reconstituted Complexphysical9990007
TRAF2Reconstituted Complexphysical9990007
SUMO1Two-hybridphysical8906799
TDP2Two-hybridphysical10764746
TDP2Affinity Capture-Westernphysical10764746
MS4A1Affinity Capture-Westernphysical9933087
TRAF3IP2Affinity Capture-Westernphysical12089335
TRAF3Two-hybridphysical7527023
TRAF3Reconstituted Complexphysical7527023
TRAF3Affinity Capture-Westernphysical7527023
TRAF3Co-crystal Structurephysical10984535
XRCC6Reconstituted Complexphysical10514012
XRCC5Reconstituted Complexphysical10514012
TRAF5Reconstituted Complexphysical8790348
TRAF3Reconstituted Complexphysical9384571
TRAF6Reconstituted Complexphysical9384571
TRAF2Two-hybridphysical9020361
TRAF2Affinity Capture-Westernphysical21282461
HSPA4Reconstituted Complexphysical12356871
HSPA4Affinity Capture-Westernphysical12356871