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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for CD40 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0002768
immune response-regulating cell surface receptor signaling pathway
IEA
GO:0006461
protein complex assembly
TAS
GO:0006954
inflammatory response
TAS
GO:0007165
signal transduction
TAS
GO:0030168
platelet activation
NAS
GO:0030890
positive regulation of B cell proliferation
IEA
GO:0032735
positive regulation of interleukin-12 production
IEA
GO:0042100
B cell proliferation
NAS
GO:0043123
positive regulation of I-kappaB kinase/NF-kappaB cascade
IEP
GO:0048304
positive regulation of isotype switching to IgG isotypes
IEA
GO:0050776
regulation of immune response
TAS
GO:0051023
regulation of immunoglobulin secretion
IEA
GO:0051607
defense response to virus
IEA
GO:0071260
cellular response to mechanical stimulus
IEP
GO:2000353
positive regulation of endothelial cell apoptosis
IDA
cellular_component
GO:0005576
extracellular region
IEA
GO:0005886
plasma membrane
ISS
GO:0005886
plasma membrane
TAS
GO:0005887
integral to plasma membrane
TAS
GO:0009897
external side of plasma membrane
IEA
GO:0035631
CD40 receptor complex
ISS
GO:0043231
intracellular membrane-bounded organelle
IEA
molecular_function
GO:0004871
signal transducer activity
TAS
GO:0004872
receptor activity
IEA
GO:0005515
protein binding
IPI
GO:0019899
enzyme binding
IPI
Protein-protein interaction details for CD40 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
UGGT1
Affinity Capture-MS
physical
17353931
CALR
Affinity Capture-MS
physical
17353931
SGK1
Affinity Capture-MS
physical
17353931
USP15
Affinity Capture-MS
physical
17353931
RFC5
Affinity Capture-MS
physical
17353931
ERP44
Affinity Capture-MS
physical
17353931
POLR2H
Affinity Capture-MS
physical
17353931
SLC30A7
Affinity Capture-MS
physical
17353931
TXN
Affinity Capture-MS
physical
17353931
DDX3X
Affinity Capture-MS
physical
17353931
RNF219
Affinity Capture-MS
physical
17353931
SLC39A7
Affinity Capture-MS
physical
17353931
FBL
Affinity Capture-MS
physical
17353931
NCOA6
Reconstituted Complex
physical
10847592
RIPK2
Affinity Capture-Western
physical
9642260
TRAF2
Co-crystal Structure
physical
10411888
TRAF3
Reconstituted Complex
physical
9990007
TRAF5
Reconstituted Complex
physical
9990007
TRAF6
Reconstituted Complex
physical
9990007
TRAF2
Reconstituted Complex
physical
9990007
SUMO1
Two-hybrid
physical
8906799
TDP2
Two-hybrid
physical
10764746
TDP2
Affinity Capture-Western
physical
10764746
MS4A1
Affinity Capture-Western
physical
9933087
TRAF3IP2
Affinity Capture-Western
physical
12089335
TRAF3
Two-hybrid
physical
7527023
TRAF3
Reconstituted Complex
physical
7527023
TRAF3
Affinity Capture-Western
physical
7527023
TRAF3
Co-crystal Structure
physical
10984535
XRCC6
Reconstituted Complex
physical
10514012
XRCC5
Reconstituted Complex
physical
10514012
TRAF5
Reconstituted Complex
physical
8790348
TRAF3
Reconstituted Complex
physical
9384571
TRAF6
Reconstituted Complex
physical
9384571
TRAF2
Two-hybrid
physical
9020361
TRAF2
Affinity Capture-Western
physical
21282461
HSPA4
Reconstituted Complex
physical
12356871
HSPA4
Affinity Capture-Western
physical
12356871