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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CD40LG (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002839positive regulation of immune response to tumor cellIEA
GO:0006916anti-apoptosisIDA
GO:0006954inflammatory responseIDA
GO:0007159leukocyte cell-cell adhesionNAS
GO:0030168platelet activationIDA
GO:0030183B cell differentiationIEA
GO:0030890positive regulation of B cell proliferationIEA
GO:0032729positive regulation of interferon-gamma productionIEA
GO:0032733positive regulation of interleukin-10 productionIEA
GO:0032735positive regulation of interleukin-12 productionIDA
GO:0042100B cell proliferationIDA
GO:0045190isotype switchingISS
GO:0045348positive regulation of MHC class II biosynthetic processIEA
GO:0050776regulation of immune responseTAS
GO:0051023regulation of immunoglobulin secretionIEA
GO:2000353positive regulation of endothelial cell apoptosisIDA
cellular_component
GO:0005576extracellular regionIEA
GO:0005615extracellular spaceIEA
GO:0005625soluble fractionTAS
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneTAS
GO:0016021integral to membraneNAS
molecular_function
GO:0005125cytokine activityIEA
GO:0005164tumor necrosis factor receptor bindingIEA
GO:0005174CD40 receptor bindingIPI

Protein-protein interaction details for CD40LG (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
HPRAffinity Capture-Westernphysical10085035
APOA1Affinity Capture-Westernphysical10085035
RNF128Affinity Capture-Westernphysical18641297
UBCAffinity Capture-Westernphysical18641297
RNF128Biochemical Activityphysical18641297