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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SETDB1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001833 inner cell mass cell proliferation IEA GO:0006355 regulation of transcription, DNA-dependent IEA GO:0016568 chromatin modification IEA cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005694 chromosome IEA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0005794 Golgi apparatus IDA GO:0005886 plasma membrane IDA molecular_function GO:0003676 nucleic acid binding IEA GO:0003677 DNA binding IEA GO:0005515 protein binding IPI GO:0008168 methyltransferase activity IEA GO:0008270 zinc ion binding IEA GO:0016740 transferase activity IEA GO:0018024 histone-lysine N-methyltransferase activity IEA

Protein-protein interaction details for SETDB1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID TRIM28 Two-hybrid physical 11959841 SUZ12 Co-purification physical 14536086 TRIM28 Affinity Capture-MS physical 11959841 HIST2H3A Reconstituted Complex physical 11959841 HIST4H4 Reconstituted Complex physical 11959841 HDAC2 Affinity Capture-Western physical 12398767 SIN3A Affinity Capture-Western physical 12398767 SIN3B Affinity Capture-Western physical 12398767 C11orf1 Two-hybrid physical 16169070 DAP Two-hybrid physical 16169070 FLYWCH1 Two-hybrid physical 16169070 PPP1R8 Two-hybrid physical 16169070 SLC38A3 Two-hybrid physical 16169070 TOB1 Two-hybrid physical 16169070 USP11 Two-hybrid physical 16169070 KDM1A Two-hybrid physical 16169070 ASAH1 Two-hybrid physical 16169070 BRIX1 Two-hybrid physical 16169070 ORAI2 Two-hybrid physical 16169070 CBX8 Two-hybrid physical 16169070 DLEU1 Two-hybrid physical 16169070 HMOX2 Two-hybrid physical 16169070 OLFML3 Two-hybrid physical 16169070 HSPB3 Two-hybrid physical 16169070 CCDC106 Two-hybrid physical 16169070 PGAM5 Two-hybrid physical 16169070 NIPSNAP3A Two-hybrid physical 16169070 AIFM1 Two-hybrid physical 16169070 PHF10 Two-hybrid physical 16169070 PLEKHA4 Two-hybrid physical 16169070 POLA2 Two-hybrid physical 16169070 MOBKL3 Two-hybrid physical 16169070 PTPRS Two-hybrid physical 16169070 QTRT1 Two-hybrid physical 16169070 S100A10 Two-hybrid physical 16169070 THAP8 Two-hybrid physical 16169070 TOLLIP Two-hybrid physical 16169070 TPI1 Two-hybrid physical 16169070 TRBV2 Two-hybrid physical 16169070 BHLHE40 Two-hybrid physical 16169070 BTBD2 Two-hybrid physical 16169070 TRIB3 Two-hybrid physical 16169070 CDK4 Two-hybrid physical 16169070 CRELD1 Two-hybrid physical 16169070 TRDMT1 Two-hybrid physical 16169070 ERH Two-hybrid physical 16169070 GIPC2 Two-hybrid physical 16169070 GPS2 Two-hybrid physical 16169070 GSTO1 Two-hybrid physical 16169070 MAD2L1BP Two-hybrid physical 16169070 MRPL44 Two-hybrid physical 16169070 PAFAH1B3 Two-hybrid physical 16169070 PCDHA4 Two-hybrid physical 16169070 PPA1 Two-hybrid physical 16169070 PRKRA Two-hybrid physical 16169070 PSMD11 Two-hybrid physical 16169070 RNF10 Two-hybrid physical 16169070 SAT1 Two-hybrid physical 16169070 SERPINB9 Two-hybrid physical 16169070 SULT1E1 Two-hybrid physical 16169070 TARDBP Two-hybrid physical 16169070 TK1 Two-hybrid physical 16169070 TTR Two-hybrid physical 16169070 ULK2 Two-hybrid physical 16169070 ZFP64 Two-hybrid physical 16169070 ZNF24 Two-hybrid physical 16169070 TXNDC9 Two-hybrid physical 16169070 BAT3 Two-hybrid physical 16169070 ECSIT Two-hybrid physical 16169070 TSC22D1 Two-hybrid physical 16169070 CDYL Affinity Capture-MS physical 19061646 UBE2I Two-hybrid physical 20936779 APC Two-hybrid physical 20936779 POU5F1 Affinity Capture-Western physical 19884257 POU5F1 Affinity Capture-Western physical 19884257 MBD1 Affinity Capture-Western physical 17066076 CBX5 Affinity Capture-MS physical 19498464 CHAF1A Affinity Capture-MS physical 19498464 CHAF1B Affinity Capture-MS physical 19498464 DNMT3A Affinity Capture-Western physical 16682412 DNMT3B Affinity Capture-Western physical 16682412 SUMO2 Affinity Capture-MS physical 19394292 ESCO2 Affinity Capture-Western physical 18501190 TAT Affinity Capture-Western physical 18498648 TAT Reconstituted Complex physical 18498648 ATF7IP Reconstituted Complex physical 15691849 ATF7IP2 Reconstituted Complex physical 15691849 ATF7IP Affinity Capture-Western physical 15691849 ATF7IP2 Affinity Capture-Western physical 15691849 HIST1H3A Biochemical Activity physical 11252719 MBD1 Two-hybrid physical 15327775 MBD1 Affinity Capture-Western physical 15327775 MBD1 Affinity Capture-Western physical 15327775 CHAF1A Affinity Capture-Western physical 15327775 CHAF1A Affinity Capture-Western physical 15327775 PCNA Affinity Capture-Western physical 15327775 NLK Co-purification physical 17952062 NLK Affinity Capture-Western physical 17952062 PPARG Reconstituted Complex physical 17952062 AKT1 Two-hybrid physical 17577629 AKT1 Reconstituted Complex physical 17577629 AKT1 Affinity Capture-Western physical 17577629 AKT2 Affinity Capture-Western physical 17577629 HIST1H3A Reconstituted Complex physical 21243721 ESCO1 Affinity Capture-Western physical 20331966 ZNF274 Affinity Capture-Western physical 21170338 ZNF274 Affinity Capture-Western physical 21170338 HTT Two-hybrid physical 15383276 MRPL44 Two-hybrid physical 21900206 PCYT2 Two-hybrid physical 21900206 GRB7 Two-hybrid physical 21900206 BID Two-hybrid physical 21900206 FAM118B Two-hybrid physical 21900206 TK1 Two-hybrid physical 21900206 CDKN1A Two-hybrid physical 21900206 CDK4 Two-hybrid physical 21900206 MAP4K5 Two-hybrid physical 21900206 SMN1 Two-hybrid physical 21900206 PSME1 Two-hybrid physical 21900206 FAM128B Two-hybrid physical 21900206 LUC7L2 Two-hybrid physical 21900206 SUMO2 Two-hybrid physical 21900206 TTR Two-hybrid physical 21900206 ANXA7 Two-hybrid physical 21900206 TSC22D1 Two-hybrid physical 21900206 UBC Affinity Capture-MS physical 18781797