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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CDC27 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000075 cell cycle checkpoint TAS GO:0000278 mitotic cell cycle TAS GO:0007091 mitotic metaphase/anaphase transition IMP GO:0007094 mitotic cell cycle spindle assembly checkpoint TAS GO:0008283 cell proliferation TAS GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process TAS GO:0051301 cell division IEA GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0070979 protein K11-linked ubiquitination IDA cellular_component GO:0005634 nucleus IDA GO:0005654 nucleoplasm TAS GO:0005680 anaphase-promoting complex IDA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0005813 centrosome IDA GO:0005819 spindle TAS GO:0005829 cytosol TAS GO:0005876 spindle microtubule IDA molecular_function GO:0005488 binding IEA GO:0005515 protein binding IPI GO:0019903 protein phosphatase binding IPI

Protein-protein interaction details for CDC27 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ANAPC1 Affinity Capture-Western physical 12956947 ANAPC10 Affinity Capture-Western physical 12956947 ANAPC11 Affinity Capture-Western physical 12956947 APC2 Affinity Capture-Western physical 12956947 APC2 Affinity Capture-Western physical 12956947 ANAPC4 Affinity Capture-Western physical 12956947 CDC20 Reconstituted Complex physical 12956947 CDH1 Reconstituted Complex physical 12956947 ANAPC4 Affinity Capture-Western physical 12956947 ANAPC5 Affinity Capture-Western physical 12956947 CDC16 Affinity Capture-Western physical 12956947 ANAPC7 Affinity Capture-Western physical 12956947 CDC23 Affinity Capture-Western physical 12956947 CDC20 Affinity Capture-Western physical 14561775 CDH1 Affinity Capture-Western physical 12956947 SPATC1 Affinity Capture-Western physical 15280373 ANAPC5 Affinity Capture-Western physical 15082755 FZR1 Affinity Capture-Western physical 12797865 CDC16 Two-hybrid physical 9405394 PPP5C Reconstituted Complex physical 9405394 SMAD3 Affinity Capture-Western physical 11691834 SMAD2 Affinity Capture-Western physical 11691834 CDC20 Affinity Capture-Western physical 12196507 PIN1 Affinity Capture-Western physical 9499405 PIN1 Far Western physical 9499405 MAD2L1 Affinity Capture-Western physical 9736712 CDC20 Affinity Capture-Western physical 9736712 CDC20 Affinity Capture-Western physical 9811605 FZR1 Affinity Capture-Western physical 9811605 ANAPC1 Co-purification physical 11076961 CDC20 Affinity Capture-Western physical 9628895 CDC20 Affinity Capture-Western physical 9628895 CDC16 Affinity Capture-Western physical 9628895 MAD2L1 Affinity Capture-Western physical 9628895 PIN1 Affinity Capture-Western physical 10037602 BUB1B Affinity Capture-Western physical 10477750 ANAPC4 Affinity Capture-Western physical 10922056 ANAPC5 Affinity Capture-Western physical 10922056 CDC16 Affinity Capture-Western physical 10922056 CDC23 Affinity Capture-Western physical 10922056 ANAPC10 Affinity Capture-Western physical 10922056 CDC26 Affinity Capture-Western physical 10922056 ANAPC11 Affinity Capture-Western physical 10922056 APC2 Affinity Capture-Western physical 10922056 ANAPC7 Affinity Capture-Western physical 10922056 CDC20 Affinity Capture-Western physical 18997788 CDKN1A Affinity Capture-Western physical 17679094 TTK Affinity Capture-Western physical 12686615 USP11 Affinity Capture-MS physical 19615732 CDH1 Affinity Capture-Western physical 16479161 CDC20 Affinity Capture-Western physical 16479161 PTTG1 Affinity Capture-Western physical 16479161 CCNB1 Affinity Capture-Western physical 16479161 CTNNB1 Reconstituted Complex physical 16510875 FZR1 Affinity Capture-Western physical 12097298 CCNB1 Affinity Capture-Western physical 12097298 ANAPC2 Affinity Capture-MS physical 14657031 ANAPC4 Affinity Capture-MS physical 14657031 ANAPC5 Affinity Capture-MS physical 14657031 CDC16 Affinity Capture-MS physical 14657031 ANAPC7 Affinity Capture-MS physical 14657031 CDC23 Affinity Capture-MS physical 14657031 ANAPC10 Affinity Capture-MS physical 14657031 CDC26 Affinity Capture-MS physical 14657031 ANAPC11 Affinity Capture-MS physical 14657031 MDC1 Reconstituted Complex physical 17827148 MDC1 Affinity Capture-Western physical 17827148 CCNA2 Biochemical Activity physical 19483727 CDC16 Affinity Capture-Western physical 9356466 MAD2L1 Affinity Capture-Western physical 9356466 MAD2L1 Affinity Capture-Western physical 9356466 CREBBP Affinity Capture-Western physical 21454660 CREBBP Affinity Capture-Western physical 21454660 CDC20 Affinity Capture-Western physical 21454660 CDH1 Affinity Capture-Western physical 20663873 CDC20 Affinity Capture-Western physical 18059335 PTTG1 Biochemical Activity physical 20080579 CCNB1 Biochemical Activity physical 20080579 HSF2 Reconstituted Complex physical 20937767 HSF2 Affinity Capture-Western physical 20937767 BUB1B Affinity Capture-MS physical 20360068 TTK Affinity Capture-Western physical 20729194 TTK Affinity Capture-Western physical 20729194 UBE2S Affinity Capture-Western physical 19822757 BUB1B Affinity Capture-Western physical 22193957 ANAPC1 Affinity Capture-MS physical 22193957 ANAPC2 Affinity Capture-MS physical 22193957 ANAPC4 Affinity Capture-MS physical 22193957 ANAPC5 Affinity Capture-MS physical 22193957 CDC16 Affinity Capture-MS physical 22193957 ANAPC7 Affinity Capture-MS physical 22193957 CDC23 Affinity Capture-MS physical 22193957 ANAPC10 Affinity Capture-MS physical 22193957 ANAPC16 Affinity Capture-MS physical 22193957 BUB1B Affinity Capture-Western physical 22193957 BUB3 Affinity Capture-Western physical 22193957 CDC20 Affinity Capture-Western physical 22193957 MAD2L1 Affinity Capture-Western physical 22193957 CCNB1 Biochemical Activity physical 22193957 PTTG1 Biochemical Activity physical 22193957 PTTG1 Affinity Capture-Western physical 22193957 CKS1B Reconstituted Complex physical 20733051