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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CDH1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001701 in utero embryonic development IEA GO:0001829 trophectodermal cell differentiation IEA GO:0006915 apoptosis TAS GO:0006921 cellular component disassembly involved in apoptosis TAS GO:0007155 cell adhesion IEA GO:0007156 homophilic cell adhesion IEA GO:0007156 homophilic cell adhesion NAS GO:0007416 synapse assembly IEA GO:0009636 response to toxin IEA GO:0010033 response to organic substance IEA GO:0016337 cell-cell adhesion IDA GO:0019538 protein metabolic process IEA GO:0021983 pituitary gland development IEA GO:0022408 negative regulation of cell-cell adhesion IMP GO:0031175 neuron projection development IEA GO:0033561 regulation of water loss via skin IEA GO:0034329 cell junction assembly TAS GO:0034332 adherens junction organization TAS GO:0042493 response to drug IEA GO:0042993 positive regulation of transcription factor import into nucleus IDA GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA GO:0045216 cell-cell junction organization TAS GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0050776 regulation of immune response TAS GO:0051260 protein homooligomerization IEA GO:0060662 salivary gland cavitation IEA GO:0060693 regulation of branching involved in salivary gland morphogenesis IEA GO:0070830 tight junction assembly IEA GO:0071230 cellular response to amino acid stimulus IEA GO:0071285 cellular response to lithium ion IDA GO:0071681 cellular response to indole-3-methanol IDA GO:2000008 regulation of protein localization at cell surface IEA cellular_component GO:0005737 cytoplasm IDA GO:0005768 endosome IEA GO:0005794 Golgi apparatus IEA GO:0005886 plasma membrane IDA GO:0005886 plasma membrane IEA GO:0005886 plasma membrane TAS GO:0005913 cell-cell adherens junction IDA GO:0005925 focal adhesion IDA GO:0009898 internal side of plasma membrane IDA GO:0009986 cell surface IEA GO:0015629 actin cytoskeleton IDA GO:0016021 integral to membrane IDA GO:0016021 integral to membrane IEA GO:0016235 aggresome IDA GO:0016323 basolateral plasma membrane IEA GO:0016328 lateral plasma membrane IDA GO:0016342 catenin complex IDA GO:0030054 cell junction IDA GO:0030054 cell junction TAS GO:0033268 node of Ranvier IEA GO:0043219 lateral loop IEA GO:0043220 Schmidt-Lanterman incisure IEA GO:0043296 apical junction complex IDA GO:0045177 apical part of cell IEA GO:0048471 perinuclear region of cytoplasm IDA molecular_function GO:0005509 calcium ion binding IEA GO:0005515 protein binding IPI GO:0008013 beta-catenin binding IEA GO:0019903 protein phosphatase binding IEA GO:0019904 protein domain specific binding IEA GO:0032794 GTPase activating protein binding IPI GO:0042153 RPTP-like protein binding IEA GO:0045295 gamma-catenin binding IPI GO:0050839 cell adhesion molecule binding NAS

Protein-protein interaction details for CDH1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CTNND1 Two-hybrid physical 7651399 CBLL1 Two-hybrid physical 11836526 HDAC1 Affinity Capture-Western physical 15388328 HDAC1 Co-purification physical 15388328 HDAC2 Co-purification physical 15388328 HDAC2 Affinity Capture-Western physical 15388328 CTNND1 Affinity Capture-Western physical 7651399 CTNNB1 Affinity Capture-Western physical 11254878 MET Affinity Capture-Western physical 11254878 SRC Affinity Capture-Western physical 10744074 CTNND1 Affinity Capture-Western physical 12427869 CTNNB1 Affinity Capture-Western physical 11712088 CTNNB1 Affinity Capture-Western physical 7954478 CTNNB1 Affinity Capture-Western physical 9405455 VCL Affinity Capture-Western physical 9405455 ITGAE Co-purification physical 12434297 MAD2L2 Reconstituted Complex physical 11459826 CTNNA1 Affinity Capture-Western physical 7542250 CTNNB1 Affinity Capture-Western physical 7542250 CTNND1 Affinity Capture-Western physical 7542250 JUP Affinity Capture-Western physical 7542250 CSE1L Affinity Capture-Western physical 12061792 CTNNB1 Affinity Capture-Western physical 12061792 CTNNB1 Affinity Capture-Western physical 9535896 CTNND1 Affinity Capture-Western physical 9535896 JUP Affinity Capture-Western physical 9535896 ACTG1 Affinity Capture-Western physical 9535896 ACTN1 Affinity Capture-Western physical 9535896 VCL Affinity Capture-Western physical 9535896 GNA13 Reconstituted Complex physical 11136230 CDH1 Co-purification physical 10910767 CDH1 Affinity Capture-Western physical 10910767 CDH3 Affinity Capture-Western physical 10910767 CDH3 Affinity Capture-Western physical 10910767 GNA12 Reconstituted Complex physical 11136230 ANAPC1 Reconstituted Complex physical 12956947 ANAPC11 Reconstituted Complex physical 12956947 APC2 Reconstituted Complex physical 12956947 CDC27 Reconstituted Complex physical 12956947 ANAPC4 Reconstituted Complex physical 12956947 CDC16 Reconstituted Complex physical 12956947 ANAPC7 Reconstituted Complex physical 12956947 CDC23 Reconstituted Complex physical 12956947 CDC26 Reconstituted Complex physical 12956947 APC2 Affinity Capture-Western physical 12956947 CDC27 Affinity Capture-Western physical 12956947 CDH3 Co-purification physical 10910767 CTNNB1 Affinity Capture-Western physical 11245482 CTNNB1 Affinity Capture-Western physical 9819408 MET Affinity Capture-Western physical 11254878 JUP Reconstituted Complex physical 8074697 NEDD9 Reconstituted Complex physical 15144564 NEDD9 Affinity Capture-Western physical 15144564 CTNNB1 Affinity Capture-Western physical 15023525 AJAP1 Affinity Capture-Western physical 14595118 CA9 Affinity Capture-Western physical 14567991 CTNNB1 Affinity Capture-Western physical 12830000 CTNND1 Two-hybrid physical 12707304 CTNNB1 Affinity Capture-Western physical 12640114 CTNND1 Affinity Capture-Western physical 12640114 FYN Affinity Capture-Western physical 12640114 CTNND1 Reconstituted Complex physical 12640114 FYN Reconstituted Complex physical 12640114 FER Reconstituted Complex physical 12640114 YES1 Reconstituted Complex physical 12640114 RAB8B Affinity Capture-Western physical 12639940 CDON Affinity Capture-Western physical 12634428 CDON Affinity Capture-Western physical 12634428 CTNNB1 Affinity Capture-Western physical 12634428 BOC Affinity Capture-Western physical 12634428 PKP4 Two-hybrid physical 12615965 CTNNA1 Affinity Capture-Western physical 11960376 CTNNB1 Affinity Capture-Western physical 11960376 EGFR Affinity Capture-Western physical 10969083 JUP Affinity Capture-Western physical 8207061 CTNNA1 Affinity Capture-Western physical 8227214 CTNNB1 Affinity Capture-Western physical 8227214 MYO7A Affinity Capture-Western physical 11080149 VEZT Affinity Capture-Western physical 11080149 CTNNB1 Affinity Capture-Western physical 9233779 CTNNA1 Affinity Capture-Western physical 9233779 MAGI1 Affinity Capture-Western physical 10772923 CTNNB1 Affinity Capture-Western physical 10772923 CTNNB1 Affinity Capture-Western physical 10772923 CTNNB1 Affinity Capture-Western physical 11113628 CTNND1 Affinity Capture-Western physical 7876318 CTNND1 Affinity Capture-Western physical 7876318 CTNNB1 Affinity Capture-Western physical 7876318 CDH1 Reconstituted Complex physical 10202138 ARPC2 Affinity Capture-Western physical 11882288 PSEN1 Affinity Capture-Western physical 10635315 CTNND1 Reconstituted Complex physical 10409703 CTNND1 Affinity Capture-Western physical 10409703 CTNNB1 Affinity Capture-Western physical 12169098 CTNNB1 Affinity Capture-Western physical 12169098 CTNNB1 Co-crystal Structure physical 11348595 JUP Affinity Capture-Western physical 1639850 CTNNA1 Affinity Capture-Western physical 10381631 CTNNB1 Affinity Capture-Western physical 10381631 EZR Affinity Capture-Western physical 10462524 IQGAP1 Affinity Capture-Western physical 10608854 IQGAP1 Reconstituted Complex physical 10608854 FOXM1 Affinity Capture-Western physical 18758239 FOXM1 Affinity Capture-Western physical 18758239 CBLL1 Affinity Capture-Western physical 11836526 UBC Affinity Capture-Western physical 18624796 CTNNB1 Affinity Capture-Western physical 18593907 MDM2 Affinity Capture-Western physical 16980628 MDM2 Affinity Capture-Western physical 16980628 MDM2 Reconstituted Complex physical 16980628 UBC Affinity Capture-Western physical 16980628 UBC Affinity Capture-Western physical 16751808 CDC27 Affinity Capture-Western physical 16479161 PTTG1 Affinity Capture-Western physical 16479161 CBLL1 Affinity Capture-Western physical 16336960 ADAM9 Affinity Capture-Western physical 16336960 CREBBP Affinity Capture-Western physical 16319895 EP300 Affinity Capture-Western physical 16319895 EP300 Affinity Capture-Western physical 16319895 CREBBP Affinity Capture-Western physical 16319895 PSEN1 Affinity Capture-Western physical 16126725 USP9X Co-fractionation physical 14742711 PIM1 Affinity Capture-Western physical 20663873 SKP2 Affinity Capture-Western physical 20663873 CDC27 Affinity Capture-Western physical 20663873 PIM1 Affinity Capture-Western physical 20663873 SRC Affinity Capture-Western physical 21685945 CBLL1 Affinity Capture-Western physical 21685945 TAS2R13 Affinity Capture-Western physical 20064487 CTNND1 Reconstituted Complex physical 20371349 CTNND1 Co-crystal Structure physical 20371349 CTNND1 Co-localization physical 20371349 NKD2 Co-fractionation physical 20177058 TK1 Biochemical Activity physical 17227951 TK1 Reconstituted Complex physical 17227951 UBC Affinity Capture-Western physical 18057010 CDC42 Reconstituted Complex physical 18057010 CDC42 Affinity Capture-Western physical 18057010 SRC Affinity Capture-Western physical 18057010 CBLL1 Co-localization physical 18057010 TACC3 Affinity Capture-Western physical 19823035 TACC3 Affinity Capture-Western physical 19823035 TACC3 Reconstituted Complex physical 19823035 TACC3 Two-hybrid physical 19823035 TTK Affinity Capture-Western physical 20729194 ZC3HC1 Affinity Capture-Western physical 22205987 ZC3HC1 Biochemical Activity physical 22205987 PIM1 Biochemical Activity physical 20663873 CDR2 Biochemical Activity physical 20383333 CCNB1 Biochemical Activity physical 20383333