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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Expression information for CHEK2 (Homo sapiens)
(Information derived after consensus based scoring of curated data)

Tissue/Sub tissueCondition/Sub ConditionExpression statusReliability scoreReferences
UterusLeiomyosarcomaNot AvailableNot Available
EndometriumEndometriosisDormant2
UterusCIN/Cervical dysplasiaDormant6
EndometriumNormalDormant10
MyometriumNormalDormant12
CervixCervical cancerDormant38
EndometriumEndometrial cancerDormant48
UterusLeiomyomaDormant62
CervixNormalDormant72
UterusNormalDormant108

NGS based expression information for CHEK2 (Homo sapiens)
(Information from literature curation)

StudyConditionExpression status
Llorens et al. Multiple platform assessment of the EGF dependent transcriptome by microarray and deep tag sequencing analysis.
BMC Genomics 2011 Jun 23;12:326.
EGF treated
vs.
untreated control HeLa cells
Down-regulated
Lebedeva et al. Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR.
Mol Cell 2011 Aug 5;43(3):340-52.
ELAVL1/HuR knock down
vs.
mock knockdown HeLa cells
Not available
Yang et al. Genomewide characterization of non-polyadenylated RNAs.
Genome Biol. 2011;12(2):R16.
Poly A(-)
vs.
ploy A(+) RNA fraction of HeLa cells
Down-regulated

EST based expression for CHEK2 (Homo sapiens)
(Information obtained from UniGene database)

UniGene cluster ID Tissue/Condition EST count Transcripts per million
Hs.291363Uterus2085
Hs.291363Cervix6124
Hs.505297Uterus00
Hs.505297Cervix00
Hs.291363Uterine tumor16177
Hs.291363Cervical tumor129
Hs.505297Uterine tumor00
Hs.505297Cervical tumor00