Entrez gene ID | | 10013 |
Official gene symbol | | HDAC6 |
Full name | | histone deacetylase 6 |
Aliases | | ,FLJ16239,HD6,JM21, |
Gene summary | | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xp11.23 |
Gene position | | 48660487 - 48683380 Map Viewer |
Gene orientation | | plus |
Gene size | | 22894 bp |
Gene sequence |
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OMIM ID | | 300272 |
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