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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HUWE1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10075
Official gene symbolHUWE1
Full nameHECT, UBA and WWE domain containing 1
Aliases,ARF-BP1,HECTH9,HSPC272,Ib772,KIAA0312,LASU1,MULE,UREB1,
Gene summaryThis gene encodes a member of the HECT E3 ubiquitin ligase family. The HECT domain lies in the C-terminus and contains the active-site cysteine which forms an intermediate ubiquitin-thioester bond. E3 family members are divided into three subfamilies based on their protein-protein interaction domains; this gene encodes a member of the SI(ngle)-HECT E3 subfamily. In lung, breast, and colorectal carcinomas, this gene is highly expressed. Mutations in this gene has been found in 3 unrelated families with X-linked syndromic mental retardation, Turner type. [provided by RefSeq]
LocationChromosome: X   Locus: Xp11.22
Gene position53713673 - 53559063  Map Viewer
Gene orientationminus
Gene size154611 bp
Gene sequence
OMIM ID300697