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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CDK2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1017 Official gene symbol CDK2 Full name cyclin-dependent kinase 2 Aliases ,p33(CDK2), Gene summary The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq] Location Chromosome: 12   Locus: 12q13 Gene position 56360556 - 56366568  Map Viewer Gene orientation plus Gene size 6013 bp Gene sequence >CDK2:18503862..18509874:Length=6013 GCGGGAAGCAGGGGCGGGGCCTCTGGTGGCGGTCGGGAACTCGGTGGGAGGCGGCAACAT TGTTTCAAGTTGGCCAAATTGACAAGAGCGAGAGGTATACTGCGTTCCATCCCGACCCGG GGCCACGGTACTGGGCCCTGTTTCCCCCTCCTCGGCCCCCGAGAGCCAGGGTCCGCCTTC TGCAGGGTTCCCAGGCCCCCGCTCCAGGGCCGGGCTGACCCGACTCGCTGGCGCTTCATG GAGAACTTCCAAAAGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCC AGAAACAAGTTGACGGGAGAGGTGGTGGCGCTTAAGAAAATCCGCCTGGACACGTGAGTG GCCTCTGTACCCGGGACTCCTAACTGGGGACCTCCTTGATTGTCCCCCCCAACCCCCCAC GGGCGGGTAGCCGTCCAGGGACCGGAAGAGAGCAGGGAGGGACTTCTTTAGAAGTGGAGA GGTGGGTTGGGGGCCAGTAGAAGGTGAAGAGTATACTTATACTCCCTGGGGAGAGTATAG GGTGGTGTGGAATCCATGGAAAACTTTCTTCCCAAACTGAGCCGGATCGTGCCCCCAAAT GTGCGACTACAGACTCGGGGAGAGAAAGGAGGTCTCTGAGATGAGGTCCAAGACTCTCCA TGGAGTGGAGTTATGTGGGAACCGGCGAGAATCGCCTTTCTGAATGAAGAGCCCTCTTCA CTGCCCCACCCTCACCTTAGAATTCTCTCCTCTTTCCAAAGAATGGCAGTTGAACCTCAC TGGCCCCTCTGGGGAGGCTGGGGGCTACTCCTGCATTTTTTCCCCTCCATTACAGTCTCC CTGCTTCACCTTCACCAGGCGGCTTTACTTACCTACCCCTGGGAAAAGAGGAGATAATGG CCTTAATATATCCAAAAACCACACCCTGACTACCCAAGAATTAGCTCTTACCATCACCCT TTCTCTTCTCTCACTTTCCTAGGGGGTGCTGGGTGGTGTCTCCTTGGGGGAAAGAAATGA CTAGGTGGGGGGGAAAGGAATATTTGTAACCATATTCCCATCTCTGCTTTCCCAACCTCT CCAAGTGAGACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAG CTTAACCATCCTAATATTGTCAAGTAAGTATGCGTCTGAGAGGTGATCCAGCTGGAAAGG AGGATAAGTTCTGTCTGTACAGTGTGGGCATTTCTCTCTCTCACACACCTCCATTTCCTC AAACTTTCCTTCTCTAGGCTGCTGGATGTCATTCACACAGAAAATAAACTCTACCTGGTT TTTGAATTTCTGCACCAAGATCTCAAGAAATTCATGGATGCCTCTGCTCTCACTGGCATT CCTCTTCCCCTCATCAAGGTAATGCTTCTCATCAGCTCCTCTCATCATGGGCATGTCTTG GGGGACTGGTGGCAGGCAATTCAGGGTGATATTTTATGATTTTGGCCTCCTTCTGAGCCC TCATCTCCTATACACACACACTCCCCTTCTTTTTGTGTCTCCTTCCCTGCTCATTATATT CATTAACCCTAGGGTTGGACTGAACAATCAAAGTTGAAACTCTAGTGAGTCAACCTAGCA ACTCAGGTGGGAGGTCAGATGAAACTCAGATAAACGGGATTTGAGAGCACTTGGTAAATT CCTCCAAAAAGCCCTTCCATTTGGTGGAAGACCTAGCTAGTGAGTCCCTATTGTCTATTT TAGGGCTGGATTCTTCACTCCCAGAGCTACTTTCAATCTATTAACAAACATTTTTTCAAT GCACAGGATGTAGAAAAGGGATGGAAAATTGAGTAAGACTTGGTCCTTATCCTCTCTGGG CTGACAGTCCATTGGGAGAAATAGCTTGTAAATATGTAACTATAATCCAACATAATAAAG GCTTTAGTAGAGTTTTAGGGGCACAGAGCAAACCCAGTCTGCTCACTGTAATGGAGAAAC ACAGTCCTCTCTTTCTCCTTTGTCAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTT TCTGCCATTCTCATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACA CAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGAGCTTTTGGAGTCCCTGTTC GTACTTACACCCATGAGGTGAGTCCCTTTATGTCTTTTTTCTCTGAGCTTCCCAAGAGGT GTTAACTAGGGTATTCACAAAGTTACTAAAAATATCTGGCTAACAGTTTCTTACTAGGTA GAAATAATCTCTTGACATCCTAAAGAGTCTTAGGGTATGCATGGAATTCATACTGTGTTG CTAACTGGGCCCACACCTGTAATACCAATACTTTGGGAGGCTGAGGTGGGAGGATCACTT GAGCCCAGGAGTTCGAGACCATCATGGGCAACATAGCGAGACCCCATCTCTACAAATCTA CAAAAAGAAAAAATTTAGAAATAAAATTATGACCAATTTGTCTCAAGTTTTTCCAGGAAG ATCTCAAATTAGGGGTTCAGTCCAGAACTATGGACTGGAAATCAGTGGGAGGGGAAAGAT GATGGAGGGAAGGAAACTGCTTGTTAAGAGGCCAAGAGTAAGCAGAGTAGTGTTGAGGAA CTGAGATGCGGGAATTTCCATACCCTATAAACCACCCCGCCCCTCCCTATTCCCGTCCCT CAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTATTCC ACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGGTATGGAGGCTTGCC CAAGTTCCACCCAGCCCCCTCCCTCTCCTCCCCACATCCAAGAACAACAGAACTGCTTCT TGGCCCAGACCTATGGCCCTTCTATCACAGGGTTCTCTCTCTAAAGTAGCACCAAGGGGA ATGGTGGGAAAGGATGCAACTGTTGCCCTGATATCAACCACAGTGTTAGGATATCCTCAA ACAGCCTTAGTACCTGGTATACATCTCTTATCCCTGAAATAAGTTAAAGCATTTCTGCAG CTGTTTTAGCTGTAGTCTGCATATATTTGGGAGAATGATTCCATTTAGTGCCTCTTTTAT TTCAGGCCTTCATTTCAAGGCTTGTAGACCTTGTTGTATGGTGCCAGCAATGTAGTGAAG ACAACTGTGGTCACTTTACCCACACCTTTCATTTAAACTGCAGATTTAGGCAGGGTGCAG TGGCTCACACCTATAATACCAGCACTTTGGGAGGCTGAGGTAGGTGGATCACCTGAGGTC AGGAGTTTGAGACCAGCCTGGCCAACATGTTAAAACCCTGTCTCTACTAAAAATACAAAA ATTAGCCAGGTGTGGCTACTTGGGATTACACACCTGTAATCCCAGCTACTTGGGAGGCCA AGGCAGGAGAATCGGTTGAACCCGGGAGATGGAGGTTGCAGTGACCAAGATTGCACCACT GCACTCCAGCCTGGGCGACAGAATGAGATTCCATCTCAAAAAAAAAAAAAAAAAAAAAAA AAAAAAGATTTAGATCATGTTCCCCTTCAACCTCTGGCTTTTCAGACTGAAGGATCCTTG AAGCCTGGCTTTATGTAGAAGCTCCCATCTCCTTTAATATAACAGTACAGTGGTGCAGTA GGCTGTCTTCAAATCAGCAATATGTTTTATTGTCTTTTATCTTGGTTGTAACCAAGAGCT TAAAGACCATTAGCCTATACATATGTAATGTGCATTTATCCCCCCAGTGCATTACCTTAC AATTGTCCGTATTCCTCTCTCAATTCATCAAAAAATATTTGTTAAGCACCTAGTGGGTAC CCAGCACCATGCTAGGTGCTGTGGGGAACACAGAAGAAATGGAAGACAGAGTCTCTGCCC GCTGTGCTCGTATCTAGAAGTGGCTGCATCACAAGGTTGGGGGATGACCGCAGTGTCTAC CCCCTACCCCGTGAGTGGCTTGGGATACCTTTGCTACATGTCAGTGGCACCCCAGACATT CACCCCCTCCCAGACCCACCCAGCCTTGGGGATCTGCAAAGCCATGGTTGGGGGAAGGAA GGAGGGGGCGAGGAGACAGATGAAGGAACTTCATTGTCTCAGGTTCTGTGTGACTGACCC CATGAAAGGCCCTGGGGAGGGAGTCATGGGGCCCTGCTGACCTTTTACTGTCTGTGGGAA CTCCTTTGTATAGAGGAGAGTTTTGACTGACGTCAACGTGGGTCTTGGTATTTCCTCTTT CCCCATTTTCAGGTGACTCGCCGGGCCCTATTCCCTGGAGATTCTGAGATTGACCAGCTC TTCCGGATCTTTCGGACTCTGGGGACCCCAGATGAGGTGGTGTGGCCAGGAGTTACTTCT ATGCCTGATTACAAGCCAAGTTTCCCCAAGTGGGCCCGGCAAGATTTTAGTAAAGTTGTA CCTCCCCTGGATGAAGATGGACGGAGCTTGTTATCGGTGAGAGTGGGCACCTGTTTTCCC TCATTCATTTCTCCCAGGGAAGGGCTTTTCCAGGATGAAGGAAGGATGAGACCCTGAAAT CTGGGCCTCAGTGTTTCATTTCCCTGGTTCCTGCTCTCCCTGTTGGCACACTGATTCAGC TATGGGAGGATGGAAGTGAGAATTCTGCCTTGGGTAGAAGGAGTTCTGGTTTCCTGATTT CTGGGAACACCTGCTGCCCATTTAGTCCACTATCACATCATTGAAGTCAACATGCATCTC TCCCTCTAGCAAATGCTGCACTACGACCCTAACAAGCGGATTTCGGCCAAGGCAGCCCTG GCTCACCCTTTCTTCCAGGATGTGACCAAGCCAGTACCCCATCTTCGACTCTGATAGCCT TCTTGAAGCCCCCAGCCCTAATCTCACCCTCTCCTCCAGTGTGGGCTTGACCAGGCTTGG CCTTGGGCTATTTGGACTCAGGTGGGCCCTCTGAACTTGCCTTAAACACTCACCTTCTAG TCTTGGCCAGCCAACTCTGGGAATACAGGGGTGAAAGGGGGGAACCAGTGAAAATGAAAG GAAGTTTCAGTATTAGATGCACTTAAGTTAGCCTCCACCACCCTTTCCCCCTTCTCTTAG TTATTGCTGAAGAGGGTTGGTATAAAAATAATTTTAAAAAAGCCTTCCTACACGTTAGAT TTGCCGTACCAATCTCTGAATGCCCCATAATTATTATTTCCAGTGTTTGGGATGACCAGG ATCCCAAGCCTCCTGCTGCCACAATGTTTATAAAGGCCAAATGATAGCGGGGGCTAAGTT GGTGCTTTTGAGAACCAAGTAAAACAAAACCACTGGGAGGAGTCTATTTTAAAGAATTCG GTTGAAAAAATAGATCCAATCAGTTTATACCCTAGTTAGTGTTTTGCCTCACCTAATAGG CTGGGAGACTGAAGACTCAGCCCGGGTGGGGCTGCAGAAAAATGATTGGCCCCAGTCCCC TTGTTTGTCCCTTCTACAGGCATGAGGAATCTGGGAGGCCCTGAGACAGGGATTGTGCTT CATTCCAATCTATTGCTTCACCATGGCCTTATGAGGCAGGTGAGAGATGTTTGAATTTTT CTCTTCCTTTTAGTATTCTTAGTTGTTCAGTTGCCAAGGATCCCTGATCCCATTTTCCTC TGACGTCCACCTCCTACCCCATAGGAGTTAGAAGTTAGGGTTTAGGCATCATTTTGAGAA TGCTGACACTTTTTCAGGGCTGTGATTGAGTGAGGGCATGGGTAAAAATATTTCTTTAAA AGAAGGATGAACAATTATATTTATATTTCAGGTTATATCCAATAGTAGAGTTGGCTTTTT TTTTTTTTTTTTGGTCATAGTGGGTGGATTTGTTGCCATGTGCACCTTGGGGTTTTGTAA TGACAGTGCTAAAAAAAAAAAGCATTTTTTTTTTATGATTTGTCTCTGTCACCCTTGTCC TTGAGTGCTCTTGCTATTAACGTTATTTGTAATTTAGTTTGTAGCTCATTAAAAAAATGT GCCTAGTTTTATA OMIM ID 116953