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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DLC1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10395
Official gene symbolDLC1
Full namedeleted in liver cancer 1
Aliases,ARHGAP7,FLJ21120,HP,STARD12,p122-RhoGAP,
Gene summaryThis gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
LocationChromosome: 8   Locus: 8p22
Gene position13372429 - 12940872  Map Viewer
Gene orientationminus
Gene size431558 bp
Gene sequence
OMIM ID604258