Entrez gene ID | | 10395 |
Official gene symbol | | DLC1 |
Full name | | deleted in liver cancer 1 |
Aliases | | ,ARHGAP7,FLJ21120,HP,STARD12,p122-RhoGAP, |
Gene summary | | This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene. |
Location | | Chromosome: 8 Locus: 8p22 |
Gene position | | 13372429 - 12940872 Map Viewer |
Gene orientation | | minus |
Gene size | | 431558 bp |
Gene sequence |
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OMIM ID | | 604258 |
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