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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for VAV3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10451
Official gene symbolVAV3
Full namevav 3 guanine nucleotide exchange factor
Aliases,FLJ40431,
Gene summaryThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p13.3
Gene position108507545 - 108113782  Map Viewer
Gene orientationminus
Gene size393764 bp
Gene sequence
OMIM ID605541