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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for VAV3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001525 angiogenesis IEA GO:0006906 vesicle fusion IEA GO:0006915 apoptosis TAS GO:0006974 response to DNA damage stimulus IMP GO:0007229 integrin-mediated signaling pathway IEA GO:0007264 small GTPase mediated signal transduction IEA GO:0007264 small GTPase mediated signal transduction TAS GO:0007596 blood coagulation TAS GO:0008624 induction of apoptosis by extracellular signals TAS GO:0016477 cell migration IEA GO:0030032 lamellipodium assembly IEA GO:0030168 platelet activation TAS GO:0030890 positive regulation of B cell proliferation IMP GO:0035023 regulation of Rho protein signal transduction IEA GO:0035556 intracellular signal transduction IEA GO:0042493 response to drug IMP GO:0043087 regulation of GTPase activity IEA GO:0043547 positive regulation of GTPase activity TAS GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IEA GO:0045785 positive regulation of cell adhesion IEA GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0050853 B cell receptor signaling pathway IMP GO:0051056 regulation of small GTPase mediated signal transduction TAS cellular_component GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS GO:0005886 plasma membrane IEA molecular_function GO:0005070 SH3/SH2 adaptor activity TAS GO:0005085 guanyl-nucleotide exchange factor activity IEA GO:0005089 Rho guanyl-nucleotide exchange factor activity IEA GO:0005096 GTPase activator activity TAS GO:0005154 epidermal growth factor receptor binding IEA GO:0005515 protein binding IPI GO:0030676 Rac guanyl-nucleotide exchange factor activity IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for VAV3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID GRB2 Affinity Capture-MS physical 12577067 PDGFRB Affinity Capture-Western physical 10938113 EGFR Affinity Capture-Western physical 10938113 RAC1 Reconstituted Complex physical 10523675 RHOA Reconstituted Complex physical 10523675 RHOG Reconstituted Complex physical 10523675 ROS1 Affinity Capture-Western physical 11094073 INSR Affinity Capture-Western physical 11094073 IGF1R Affinity Capture-Western physical 11094073 GRB2 Affinity Capture-Western physical 11094073 SHC1 Affinity Capture-Western physical 11094073 GRB2 Two-hybrid physical 20936779