Entrez gene ID | | 10603 |
Official gene symbol | | SH2B2 |
Full name | | SH2B adaptor protein 2 |
Aliases | | ,APS, |
Gene summary | | The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq] |
Location | | Chromosome: 7 Locus: 7q22 |
Gene position | | 101928405 - 101962178 Map Viewer |
Gene orientation | | plus |
Gene size | | 33774 bp |
Gene sequence |
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OMIM ID | | 605300 |
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