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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SH2B2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID10603
Official gene symbolSH2B2
Full nameSH2B adaptor protein 2
Aliases,APS,
Gene summaryThe protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q22
Gene position101928405 - 101962178  Map Viewer
Gene orientationplus
Gene size33774 bp
Gene sequence
OMIM ID605300