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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for SH2B2 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001922
B-1 B cell homeostasis
IEA
GO:0007165
signal transduction
TAS
GO:0007399
nervous system development
IEA
GO:0007596
blood coagulation
TAS
GO:0008286
insulin receptor signaling pathway
IEA
GO:0008286
insulin receptor signaling pathway
ISS
GO:0019221
cytokine-mediated signaling pathway
IEA
GO:0019222
regulation of metabolic process
IEA
GO:0030036
actin cytoskeleton organization
IEA
GO:0035556
intracellular signal transduction
IDA
GO:0035556
intracellular signal transduction
IEA
GO:0046425
regulation of JAK-STAT cascade
IDA
GO:0046578
regulation of Ras protein signal transduction
IEA
GO:0050776
regulation of immune response
IEA
GO:0050851
antigen receptor-mediated signaling pathway
IEA
GO:0050873
brown fat cell differentiation
IEA
cellular_component
GO:0001725
stress fiber
IEA
GO:0001726
ruffle
IEA
GO:0005737
cytoplasm
IDA
GO:0005829
cytosol
TAS
GO:0005884
actin filament
IEA
GO:0005886
plasma membrane
IDA
molecular_function
GO:0004871
signal transducer activity
IEA
GO:0005068
transmembrane receptor protein tyrosine kinase adaptor activity
IEA
GO:0005070
SH3/SH2 adaptor activity
IDA
GO:0005070
SH3/SH2 adaptor activity
IEA
GO:0008269
JAK pathway signal transduction adaptor activity
IDA
Protein-protein interaction details for SH2B2 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
JAK2
Biochemical Activity
physical
10374881
CBL
Reconstituted Complex
physical
10374881
NTRK1
Two-hybrid
physical
9856458
NTRK1
Affinity Capture-Western
physical
9856458
GRB2
Affinity Capture-Western
physical
9856458
CBL
Affinity Capture-Western
physical
18273061
CBL
Co-crystal Structure
physical
15737992
CBL
Affinity Capture-Western
physical
15737992