Entrez gene ID | | 11065 |
Official gene symbol | | UBE2C |
Full name | | ubiquitin-conjugating enzyme E2C |
Aliases | | ,UBCH10,dJ447F3.2, |
Gene summary | | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20q13.12 |
Gene position | | 44441255 - 44445596 Map Viewer |
Gene orientation | | plus |
Gene size | | 4342 bp |
Gene sequence |
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OMIM ID | | 605574 |
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