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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for UBE2C (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000075 cell cycle checkpoint TAS GO:0000278 mitotic cell cycle TAS GO:0006511 ubiquitin-dependent protein catabolic process IDA GO:0007049 cell cycle NAS GO:0007051 spindle organization NAS GO:0007067 mitosis IEA GO:0007094 mitotic cell cycle spindle assembly checkpoint TAS GO:0008054 cyclin catabolic process IDA GO:0010458 exit from mitosis IMP GO:0010994 free ubiquitin chain polymerization IDA GO:0016567 protein ubiquitination IDA GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process IDA GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process TAS GO:0031536 positive regulation of exit from mitosis IMP GO:0048015 phosphatidylinositol-mediated signaling NAS GO:0051301 cell division IEA GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051488 activation of anaphase-promoting complex activity TAS GO:0070936 protein K48-linked ubiquitination IDA GO:0070979 protein K11-linked ubiquitination IDA cellular_component GO:0005654 nucleoplasm TAS GO:0005680 anaphase-promoting complex IDA GO:0005829 cytosol TAS molecular_function GO:0000166 nucleotide binding IEA GO:0004842 ubiquitin-protein ligase activity IDA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016874 ligase activity IEA GO:0016881 acid-amino acid ligase activity IEA

Protein-protein interaction details for UBE2C (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID RNF216 Affinity Capture-Western physical 15107846 ENO2 Two-hybrid physical 16169070 ANAPC2 Reconstituted Complex physical 11739784 POLM Biochemical Activity physical 17588522 UBASH3B Biochemical Activity physical 17588522 ANAPC2 Co-fractionation physical 17443186 CDC20 Co-fractionation physical 17443186 MAD2L1 Co-fractionation physical 17443186 BUB1B Co-fractionation physical 17443186 DTX1 Two-hybrid physical 19690564 UBC Affinity Capture-MS physical 16196087 UBC Reconstituted Complex physical 19475398 UBC Reconstituted Complex physical 21965653 UBC Affinity Capture-MS physical 20639865 UBE2CBP Reconstituted Complex physical 15749827