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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IRAK3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11213
Official gene symbolIRAK3
Full nameinterleukin-1 receptor-associated kinase 3
Aliases,ASRT5,FLJ13601,IRAKM,
Gene summaryThis gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q14.3
Gene position66582978 - 66648402  Map Viewer
Gene orientationplus
Gene size65425 bp
Gene sequence
OMIM ID604459