| Entrez gene ID | | 1270 |
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| Official gene symbol | | CNTF |
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| Full name | | ciliary neurotrophic factor |
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| Aliases | | ,HCNTF, |
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| Gene summary | | The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq] |
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| Location | | Chromosome: 11 Locus: 11q12.2 |
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| Gene position | | 58390146 - 58393206 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 3061 bp |
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| Gene sequence |
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| OMIM ID | | 118945 |
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