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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CNTF (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0007165 signal transduction NAS GO:0007275 multicellular organismal development IEA GO:0007399 nervous system development IEA GO:0008284 positive regulation of cell proliferation IEA GO:0014068 positive regulation of phosphatidylinositol 3-kinase cascade IEA GO:0030154 cell differentiation IEA GO:0030307 positive regulation of cell growth IEA GO:0040007 growth IEA GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein IDA GO:0043410 positive regulation of MAPKKK cascade IEA GO:0043524 negative regulation of neuron apoptosis IDA GO:0043526 neuroprotection IEA GO:0046427 positive regulation of JAK-STAT cascade IEA GO:0046533 negative regulation of photoreceptor cell differentiation IEA GO:0046668 regulation of retinal cell programmed cell death IEA GO:0046887 positive regulation of hormone secretion IEA GO:0048143 astrocyte activation IEA GO:0048644 muscle organ morphogenesis IEA GO:0048666 neuron development IEA GO:0048680 positive regulation of axon regeneration IEA GO:0060075 regulation of resting membrane potential IEA GO:0060081 membrane hyperpolarization IEA GO:0070120 ciliary neurotrophic factor-mediated signaling pathway IDA cellular_component GO:0005615 extracellular space IC GO:0005634 nucleus IEA GO:0005737 cytoplasm IEA GO:0005829 cytosol IEA GO:0030424 axon IEA GO:0032838 cell projection cytoplasm IEA GO:0043025 neuronal cell body IEA GO:0043231 intracellular membrane-bounded organelle IDA molecular_function GO:0005125 cytokine activity IEA GO:0005127 ciliary neurotrophic factor receptor binding IEA GO:0005138 interleukin-6 receptor binding IPI GO:0008083 growth factor activity IDA

Protein-protein interaction details for CNTF (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID STK16 Affinity Capture-MS physical 17353931 ICA1 Affinity Capture-MS physical 17353931 EXT1 Affinity Capture-MS physical 17353931 VHL Affinity Capture-MS physical 17353931 EIF3E Affinity Capture-MS physical 17353931 EXT2 Affinity Capture-MS physical 17353931 IL6R Reconstituted Complex physical 12643274 IL6R Affinity Capture-Western physical 12643274 IL6R Reconstituted Complex physical 1281789 CNTF Co-crystal Structure physical 7796798 CNTFR Reconstituted Complex physical 7810882