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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PARP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID142
Official gene symbolPARP1
Full namepoly (ADP-ribose) polymerase 1
Aliases,ADPRT,ADPRT 1,ADPRT1,PARP,PARP-1,PPOL,pADPRT-1,
Gene summaryThis gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q41-q42
Gene position226595801 - 226548392  Map Viewer
Gene orientationminus
Gene size47410 bp
Gene sequence
OMIM ID173870