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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ADRA2C (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 152 Official gene symbol ADRA2C Full name adrenergic, alpha-2C-, receptor Aliases ,ADRA2L2,ADRA2RL2,ADRARL2,ALPHA2CAR, Gene summary Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq] Location Chromosome: 4   Locus: 4p16 Gene position 3768296 - 3770253  Map Viewer Gene orientation plus Gene size 1958 bp Gene sequence >ADRA2C:2289650..2291607:Length=1958 CCGGCTCCAGGAGGGACGGCGTAGCTCGCGGGAGGACCATGGCGTCCCCGGCGCTGGCGG CGGCGCTGGCGGTGGCGGCAGCGGCGGGCCCCAATGCGAGCGGCGCGGGCGAGAGGGGCA GCGGCGGGGTTGCCAATGCCTCGGGGGCTTCCTGGGGGCCGCCGCGCGGCCAGTACTCGG CGGGCGCGGTGGCAGGGCTGGCTGCCGTGGTGGGCTTCCTCATCGTCTTCACCGTGGTGG GCAACGTGCTGGTGGTGATCGCCGTGCTGACCAGCCGGGCGCTGCGCGCGCCACAGAACC TCTTCCTGGTGTCGCTGGCCTCGGCCGACATCCTGGTGGCCACGCTGGTCATGCCCTTCT CGTTGGCCAACGAGCTCATGGCCTACTGGTACTTCGGGCAGGTGTGGTGCGGCGTGTACC TGGCGCTCGATGTGCTGTTTTGCACCTCGTCGATCGTGCATCTGTGTGCCATCAGCCTGG ACCGCTACTGGTCGGTGACGCAGGCCGTCGAGTACAACCTGAAGCGCACACCACGCCGCG TCAAGGCCACCATCGTGGCCGTGTGGCTCATCTCGGCCGTCATCTCCTTCCCGCCGCTGG TCTCGCTCTACCGCCAGCCCGACGGCGCCGCCTACCCGCAGTGCGGCCTCAACGACGAGA CCTGGTACATCCTGTCCTCCTGCATCGGCTCCTTCTTCGCGCCCTGCCTCATCATGGGCC TGGTCTACGCGCGCATCTACCGAGTGGCCAAGCTGCGCACGCGCACGCTCAGCGAGAAGC GCGCCCCCGTGGGCCCCGACGGTGCGTCCCCGACTACCGAAAACGGGCTGGGCGCGGCGG CAGGCGCAGGCGAGAACGGGCACTGCGCGCCCCCGCCCGCCGACGTGGAGCCGGACGAGA GCAGCGCAGCGGCCGAGAGGCGGCGGCGCCGGGGCGCGTTGCGGCGGGGCGGGCGGCGGC GAGCGGGCGCGGAGGGGGGCGCGGGCGGTGCGGACGGGCAGGGGGCGGGGCCGGGGGCGG CTGAGTCGGGGGCGCTGACCGCCTCCAGGTCCCCGGGGCCCGGTGGCCGCCTGTCGCGCG CCAGCTCGCGCTCCGTCGAGTTCTTCCTGTCGCGCCGGCGCCGGGCGCGCAGCAGCGTGT GCCGCCGCAAGGTGGCCCAGGCGCGCGAGAAGCGCTTCACCTTTGTGCTGGCTGTGGTCA TGGGCGTGTTCGTGCTCTGCTGGTTCCCCTTCTTCTTCAGCTACAGCCTGTACGGCATCT GCCGCGAGGCCTGCCAGGTGCCCGGCCCGCTCTTCAAGTTCTTCTTCTGGATCGGCTACT GCAACAGCTCGCTCAACCCGGTCATCTACACGGTCTTCAACCAGGATTTCCGGCGATCCT TTAAGCACATCCTCTTCCGACGGAGGAGAAGGGGCTTCAGGCAGTGACTCGCACCCGTCT GGGAATCCTGGACAGCTCCGCGCTCGGGGCTGGGCAGAAGGGGCGGCCCGGACGGGGGAG CTTTCCCAGAGACCCGGGGATGGATTGGCCTCCAGGGCGCAGGGGAGGGTGCGGCAGGGC AGGAGCTTGGCAGAGAGATAGCCGGGCTCCAGGGAGTGGGGAGGAGAGAGGGGGAGACCC CTTTGCCTTCCCCCCTCAGCAAGGGGCTGCTTCTGGGGCTCCCTGCCTGGATCCAGCTCT GGGAGCCCTGCCGAGGTGTGGCTGTGAGGTCAGGGTTTTAGAGAGCAGTGGCAGAGGTAG CCCCCTAAATGGGCAAGCAAGGAGCCCCCCAAAGACACTACCACTCCCCATCCCCGTCTG ACCAAGGGCTGACTTCTCCAGGACCTAGTCGGGGGGTGGCTGCCAGGGGGCAAGGAGAAA GCACCGACAATCTTTGATTACTGAAAGTATTTAAATGTTTGCCAAAAACAACAGCCAAAA CAACCAAACTATTTTCTAAATAAACCTTTGTAATCTAA OMIM ID 104250