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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ADRA2C (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006112energy reserve metabolic processTAS
GO:0007186G-protein coupled receptor protein signaling pathwayTAS
GO:0007267cell-cell signalingTAS
GO:0007596blood coagulationTAS
GO:0010700negative regulation of norepinephrine secretionNAS
GO:0010700negative regulation of norepinephrine secretionTAS
GO:0032148activation of protein kinase B activityIDA
GO:0032811negative regulation of epinephrine secretionNAS
GO:0035625epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayIDA
GO:0045666positive regulation of neuron differentiationIDA
GO:0050796regulation of insulin secretionTAS
GO:0071883activation of MAPK activity by adrenergic receptor signaling pathwayIDA
cellular_component
GO:0005737cytoplasmIDA
GO:0005768endosomeTAS
GO:0005886plasma membraneIEA
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneIDA
GO:0016021integral to membraneIEA
GO:0030424axonIEA
molecular_function
GO:0004871signal transducer activityIEA
GO:0004872receptor activityIEA
GO:0004930G-protein coupled receptor activityIEA
GO:0004935adrenergic receptor activityIEA
GO:0004938alpha2-adrenergic receptor activityIDA
GO:0004938alpha2-adrenergic receptor activityIEA
GO:0005515protein bindingIPI
GO:0031694alpha-2A adrenergic receptor bindingIPI
GO:0042803protein homodimerization activityIDA
GO:0046982protein heterodimerization activityIPI
GO:0051379epinephrine bindingIDA

Protein-protein interaction details for ADRA2C (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
EIF2B1Reconstituted Complexphysical9235896
PPP1R9BReconstituted Complexphysical11154706