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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for EGFR (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1956
Official gene symbolEGFR
Full nameepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Aliases,ERBB,ERBB1,HER1,PIG61,mENA,
Gene summaryThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 7   Locus: 7p12
Gene position55086725 - 55275031  Map Viewer
Gene orientationplus
Gene size188307 bp
Gene sequence
OMIM ID131550