Entrez gene ID | | 1969 |
Official gene symbol | | EPHA2 |
Full name | | EPH receptor A2 |
Aliases | | ,ARCC2,ECK, |
Gene summary | | This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders. |
Location | | Chromosome: 1 Locus: 1p36 |
Gene position | | 16482582 - 16450832 Map Viewer |
Gene orientation | | minus |
Gene size | | 31751 bp |
Gene sequence |
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OMIM ID | | 176946 |
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