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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for EPHA2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001501 skeletal system development IEA GO:0001568 blood vessel development IEA GO:0001570 vasculogenesis IEA GO:0001649 osteoblast differentiation ISS GO:0006915 apoptosis IDA GO:0007275 multicellular organismal development TAS GO:0010591 regulation of lamellipodium assembly IMP GO:0014028 notochord formation IEA GO:0021915 neural tube development IEA GO:0030182 neuron differentiation IEA GO:0030216 keratinocyte differentiation IMP GO:0030316 osteoclast differentiation ISS GO:0032863 activation of Rac GTPase activity IMP GO:0033598 mammary gland epithelial cell proliferation ISS GO:0033628 regulation of cell adhesion mediated by integrin IDA GO:0035121 tail morphogenesis IEA GO:0043491 protein kinase B signaling cascade IDA GO:0043535 regulation of blood vessel endothelial cell migration ISS GO:0045765 regulation of angiogenesis ISS GO:0046849 bone remodeling ISS GO:0048013 ephrin receptor signaling pathway IDA GO:0048320 axial mesoderm formation IEA GO:0051898 negative regulation of protein kinase B signaling cascade IDA GO:0060035 notochord cell development IEA GO:0060326 cell chemotaxis IMP GO:0060444 branching involved in mammary gland duct morphogenesis ISS GO:0070309 lens fiber cell morphogenesis ISS GO:0070372 regulation of ERK1 and ERK2 cascade IMP GO:0070848 response to growth factor stimulus IMP GO:0090004 positive regulation of establishment of protein localization in plasma membrane IMP cellular_component GO:0005886 plasma membrane IDA GO:0005887 integral to plasma membrane IDA GO:0005925 focal adhesion IDA GO:0030054 cell junction IEA GO:0031256 leading edge membrane IDA GO:0031258 lamellipodium membrane IEA GO:0032587 ruffle membrane IEA GO:0042995 cell projection IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004714 transmembrane receptor protein tyrosine kinase activity IDA GO:0004872 receptor activity IEA GO:0005003 ephrin receptor activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA

Protein-protein interaction details for EPHA2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SLA Two-hybrid physical 7543898 SLA Affinity Capture-Western physical 7543898 SLA Reconstituted Complex physical 7543898 SHC1 Affinity Capture-Western physical 12400011 GRB2 Affinity Capture-Western physical 12400011 GRB2 Reconstituted Complex physical 12400011 SHC1 Reconstituted Complex physical 12400011 PIK3R1 Reconstituted Complex physical 7982920 PIK3R1 Affinity Capture-Western physical 7982920 PIK3R1 Two-hybrid physical 7982920 PTK2 Affinity Capture-Western physical 10655584 PTPN11 Affinity Capture-Western physical 10655584 ACP1 Affinity Capture-Western physical 12167657 ACP1 Affinity Capture-Western physical 12167657 ACP1 Biochemical Activity physical 12167657 UBC Affinity Capture-MS physical 21987572