Entrez gene ID | | 208 |
Official gene symbol | | AKT2 |
Full name | | v-akt murine thymoma viral oncogene homolog 2 |
Aliases | | ,PKBB,PKBBETA,PRKBB,RAC-BETA, |
Gene summary | | This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19q13.1-q13.2 |
Gene position | | 40791265 - 40736224 Map Viewer |
Gene orientation | | minus |
Gene size | | 55042 bp |
Gene sequence |
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OMIM ID | | 164731 |