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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for AKT2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006464 protein modification process TAS GO:0006970 response to osmotic stress IEA GO:0007165 signal transduction TAS GO:0008286 insulin receptor signaling pathway IMP GO:0008286 insulin receptor signaling pathway TAS GO:0009967 positive regulation of signal transduction IEA GO:0010628 positive regulation of gene expression IEA GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport IMP GO:0010765 positive regulation of sodium ion transport IEA GO:0010907 positive regulation of glucose metabolic process IMP GO:0014850 response to muscle activity IEA GO:0016310 phosphorylation TAS GO:0030334 regulation of cell migration TAS GO:0030335 positive regulation of cell migration IEA GO:0032000 positive regulation of fatty acid beta-oxidation IMP GO:0032869 cellular response to insulin stimulus IEA GO:0032869 cellular response to insulin stimulus IMP GO:0032870 cellular response to hormone stimulus IEA GO:0033119 negative regulation of RNA splicing IEA GO:0033138 positive regulation of peptidyl-serine phosphorylation IEA GO:0043066 negative regulation of apoptosis IEA GO:0043154 negative regulation of caspase activity IEA GO:0043491 protein kinase B signaling cascade IEA GO:0045429 positive regulation of nitric oxide biosynthetic process IEA GO:0045444 fat cell differentiation TAS GO:0045725 positive regulation of glycogen biosynthetic process IMP GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0046326 positive regulation of glucose import IEA GO:0046326 positive regulation of glucose import IMP GO:0046328 regulation of JNK cascade IEA GO:0050927 positive regulation of positive chemotaxis IEA GO:0060644 mammary gland epithelial cell differentiation TAS GO:0070887 cellular response to chemical stimulus IEA GO:0071156 regulation of cell cycle arrest TAS GO:2000147 positive regulation of cell motility IMP cellular_component GO:0005625 soluble fraction IEA GO:0005634 nucleus IDA GO:0005634 nucleus TAS GO:0005654 nucleoplasm IEA GO:0005739 mitochondrion IEA GO:0005792 microsome IEA GO:0005829 cytosol IEA GO:0005829 cytosol TAS GO:0005886 plasma membrane IEA GO:0005886 plasma membrane TAS GO:0030027 lamellipodium IEA GO:0031982 vesicle IEA GO:0032593 insulin-responsive compartment IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004672 protein kinase activity IEA GO:0004674 protein serine/threonine kinase activity IDA GO:0004674 protein serine/threonine kinase activity IEA GO:0004674 protein serine/threonine kinase activity TAS GO:0005080 protein kinase C binding IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IDA GO:0005524 ATP binding IEA GO:0016301 kinase activity TAS GO:0016772 transferase activity, transferring phosphorus-containing groups IEA

Protein-protein interaction details for AKT2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID APPL1 Two-hybrid physical 10490823 SH3RF1 Two-hybrid physical 14504284 SH3RF1 Reconstituted Complex physical 14504284 GSK3B Co-crystal Structure physical 12434148 TCL1A Affinity Capture-Western physical 11707444 CHUK Affinity Capture-Western physical 12048203 CHUK Biochemical Activity physical 12048203 PRKDC Biochemical Activity physical 16221682 TCL1A Two-hybrid physical 10983986 TCL1B Two-hybrid physical 10983986 MTCP1 Two-hybrid physical 10983986 TCL1A Affinity Capture-Western physical 10983986 APPL1 Affinity Capture-Western physical 10490823 APPL1 Reconstituted Complex physical 10490823 XIAP Biochemical Activity physical 14645242 SETDB1 Affinity Capture-Western physical 17577629 TTC3 Affinity Capture-Western physical 20059950 ESR1 Biochemical Activity physical 11507039 ESR1 Affinity Capture-Western physical 11507039