Entrez gene ID | | 2147 |
Official gene symbol | | F2 |
Full name | | coagulation factor II (thrombin) |
Aliases | | ,PT, |
Gene summary | | Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11p11 |
Gene position | | 46740743 - 46761056 Map Viewer |
Gene orientation | | plus |
Gene size | | 20314 bp |
Gene sequence |
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OMIM ID | | 176930 |