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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for F2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001934 positive regulation of protein phosphorylation IDA GO:0006508 proteolysis IEA GO:0006508 proteolysis TAS GO:0006915 apoptosis TAS GO:0006919 activation of caspase activity TAS GO:0006953 acute-phase response IEA GO:0007166 cell surface receptor linked signaling pathway IDA GO:0007260 tyrosine phosphorylation of STAT protein TAS GO:0007262 STAT protein import into nucleus TAS GO:0007275 multicellular organismal development TAS GO:0007596 blood coagulation IEA GO:0007596 blood coagulation TAS GO:0007597 blood coagulation, intrinsic pathway TAS GO:0008284 positive regulation of cell proliferation IEA GO:0008360 regulation of cell shape IEA GO:0009611 response to wounding IDA GO:0010544 negative regulation of platelet activation TAS GO:0017187 peptidyl-glutamic acid carboxylation TAS GO:0030168 platelet activation IDA GO:0030168 platelet activation TAS GO:0030193 regulation of blood coagulation TAS GO:0030194 positive regulation of blood coagulation IDA GO:0030307 positive regulation of cell growth IEA GO:0032967 positive regulation of collagen biosynthetic process IDA GO:0042730 fibrinolysis IDA GO:0043687 post-translational protein modification TAS GO:0044267 cellular protein metabolic process TAS GO:0045861 negative regulation of proteolysis IDA GO:0048712 negative regulation of astrocyte differentiation IDA GO:0050900 leukocyte migration TAS GO:0051281 positive regulation of release of sequestered calcium ion into cytosol IDA GO:0051480 cytosolic calcium ion homeostasis IDA GO:0051918 negative regulation of fibrinolysis TAS GO:2000379 positive regulation of reactive oxygen species metabolic process IDA cellular_component GO:0005576 extracellular region IEA GO:0005576 extracellular region TAS GO:0005615 extracellular space IDA GO:0005625 soluble fraction TAS GO:0005788 endoplasmic reticulum lumen TAS GO:0005796 Golgi lumen TAS GO:0005829 cytosol IDA GO:0005886 plasma membrane TAS molecular_function GO:0004252 serine-type endopeptidase activity IDA GO:0004252 serine-type endopeptidase activity IEA GO:0005102 receptor binding IPI GO:0005509 calcium ion binding IEA GO:0005515 protein binding IPI GO:0008083 growth factor activity TAS GO:0008233 peptidase activity IEA GO:0070053 thrombospondin receptor activity IDA

Protein-protein interaction details for F2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SERPINE1 Reconstituted Complex physical 12709053 FGA Co-crystal Structure physical 1587268 SERPIND1 Co-crystal Structure physical 12169660 ITGA2B Reconstituted Complex physical 11487023 PLAT Co-crystal Structure physical 10543954 CPB2 Reconstituted Complex physical 8663147 THBD Reconstituted Complex physical 8663147 SERPINB6 Reconstituted Complex physical 8415716 THBD Reconstituted Complex physical 2544585 F5 Reconstituted Complex physical 9032460 SERPING1 Reconstituted Complex physical 11460008 THBS1 Reconstituted Complex physical 2435757