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Gene information for F2RL1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2150
Official gene symbolF2RL1
Full namecoagulation factor II (thrombin) receptor-like 1
Aliases,GPR11,PAR2,
Gene summaryCoagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q13
Gene position76114833 - 76131140  Map Viewer
Gene orientationplus
Gene size16308 bp
Gene sequence
OMIM ID600933