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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for F2RL1 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0002286
T cell activation involved in immune response
ISS
GO:0002690
positive regulation of leukocyte chemotaxis
IDA
GO:0002741
positive regulation of cytokine secretion involved in immune response
IDA
GO:0006954
inflammatory response
IEA
GO:0007186
G-protein coupled receptor protein signaling pathway
IMP
GO:0007186
G-protein coupled receptor protein signaling pathway
ISS
GO:0007204
elevation of cytosolic calcium ion concentration
IDA
GO:0007204
elevation of cytosolic calcium ion concentration
ISS
GO:0010804
negative regulation of tumor necrosis factor-mediated signaling pathway
IDA
GO:0014068
positive regulation of phosphatidylinositol 3-kinase cascade
ISS
GO:0030193
regulation of blood coagulation
IDA
GO:0030335
positive regulation of cell migration
ISS
GO:0030836
positive regulation of actin filament depolymerization
IDA
GO:0031274
positive regulation of pseudopodium assembly
ISS
GO:0032930
positive regulation of superoxide anion generation
IDA
GO:0034137
positive regulation of toll-like receptor 2 signaling pathway
IMP
GO:0034140
negative regulation of toll-like receptor 3 signaling pathway
IMP
GO:0034141
positive regulation of toll-like receptor 3 signaling pathway
IMP
GO:0034145
positive regulation of toll-like receptor 4 signaling pathway
IDA
GO:0035025
positive regulation of Rho protein signal transduction
IMP
GO:0035025
positive regulation of Rho protein signal transduction
ISS
GO:0035926
chemokine (C-C motif) ligand 2 secretion
IDA
GO:0042119
neutrophil activation
IDA
GO:0043122
regulation of I-kappaB kinase/NF-kappaB cascade
IDA
GO:0043123
positive regulation of I-kappaB kinase/NF-kappaB cascade
IDA
GO:0043311
positive regulation of eosinophil degranulation
IDA
GO:0045087
innate immune response
IEA
GO:0045909
positive regulation of vasodilation
ISS
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IDA
GO:0046328
regulation of JNK cascade
IDA
GO:0046329
negative regulation of JNK cascade
IDA
GO:0046330
positive regulation of JNK cascade
IDA
GO:0050702
interleukin-1 beta secretion
IDA
GO:0050900
leukocyte migration
IDA
GO:0050921
positive regulation of chemotaxis
ISS
GO:0050927
positive regulation of positive chemotaxis
IDA
GO:0051607
defense response to virus
IDA
GO:0060100
positive regulation of phagocytosis, engulfment
IDA
GO:0061028
establishment of endothelial barrier
IDA
GO:0070374
positive regulation of ERK1 and ERK2 cascade
IDA
GO:0070374
positive regulation of ERK1 and ERK2 cascade
ISS
GO:0070963
positive regulation of neutrophil mediated killing of gram-negative bacterium
IDA
GO:0072608
interleukin-10 secretion
IDA
GO:0090195
chemokine secretion
IDA
GO:0090198
negative regulation of chemokine secretion
IDA
GO:0097029
mature dendritic cell differentiation
IDA
GO:0097029
mature dendritic cell differentiation
ISS
GO:2000484
positive regulation of interleukin-8 secretion
IDA
GO:2000778
positive regulation of interleukin-6 secretion
IDA
cellular_component
GO:0005794
Golgi apparatus
TAS
GO:0005886
plasma membrane
TAS
GO:0005887
integral to plasma membrane
IDA
GO:0016021
integral to membrane
IEA
GO:0031143
pseudopodium
ISS
molecular_function
GO:0001965
G-protein alpha-subunit binding
ISS
GO:0004871
signal transducer activity
IEA
GO:0004872
receptor activity
IEA
GO:0004930
G-protein coupled receptor activity
IMP
GO:0004930
G-protein coupled receptor activity
ISS
GO:0005102
receptor binding
TAS
GO:0005515
protein binding
IPI
GO:0015057
thrombin receptor activity
IEA
GO:0031681
G-protein beta-subunit binding
ISS
Protein-protein interaction details for F2RL1 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
UBC
Affinity Capture-Western
physical
15708858