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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for F2RL1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002286T cell activation involved in immune responseISS
GO:0002690positive regulation of leukocyte chemotaxisIDA
GO:0002741positive regulation of cytokine secretion involved in immune responseIDA
GO:0006954inflammatory responseIEA
GO:0007186G-protein coupled receptor protein signaling pathwayIMP
GO:0007186G-protein coupled receptor protein signaling pathwayISS
GO:0007204elevation of cytosolic calcium ion concentrationIDA
GO:0007204elevation of cytosolic calcium ion concentrationISS
GO:0010804negative regulation of tumor necrosis factor-mediated signaling pathwayIDA
GO:0014068positive regulation of phosphatidylinositol 3-kinase cascadeISS
GO:0030193regulation of blood coagulationIDA
GO:0030335positive regulation of cell migrationISS
GO:0030836positive regulation of actin filament depolymerizationIDA
GO:0031274positive regulation of pseudopodium assemblyISS
GO:0032930positive regulation of superoxide anion generationIDA
GO:0034137positive regulation of toll-like receptor 2 signaling pathwayIMP
GO:0034140negative regulation of toll-like receptor 3 signaling pathwayIMP
GO:0034141positive regulation of toll-like receptor 3 signaling pathwayIMP
GO:0034145positive regulation of toll-like receptor 4 signaling pathwayIDA
GO:0035025positive regulation of Rho protein signal transductionIMP
GO:0035025positive regulation of Rho protein signal transductionISS
GO:0035926chemokine (C-C motif) ligand 2 secretionIDA
GO:0042119neutrophil activationIDA
GO:0043122regulation of I-kappaB kinase/NF-kappaB cascadeIDA
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIDA
GO:0043311positive regulation of eosinophil degranulationIDA
GO:0045087innate immune responseIEA
GO:0045909positive regulation of vasodilationISS
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0046328regulation of JNK cascadeIDA
GO:0046329negative regulation of JNK cascadeIDA
GO:0046330positive regulation of JNK cascadeIDA
GO:0050702interleukin-1 beta secretionIDA
GO:0050900leukocyte migrationIDA
GO:0050921positive regulation of chemotaxisISS
GO:0050927positive regulation of positive chemotaxisIDA
GO:0051607defense response to virusIDA
GO:0060100positive regulation of phagocytosis, engulfmentIDA
GO:0061028establishment of endothelial barrierIDA
GO:0070374positive regulation of ERK1 and ERK2 cascadeIDA
GO:0070374positive regulation of ERK1 and ERK2 cascadeISS
GO:0070963positive regulation of neutrophil mediated killing of gram-negative bacteriumIDA
GO:0072608interleukin-10 secretionIDA
GO:0090195chemokine secretionIDA
GO:0090198negative regulation of chemokine secretionIDA
GO:0097029mature dendritic cell differentiationIDA
GO:0097029mature dendritic cell differentiationISS
GO:2000484positive regulation of interleukin-8 secretionIDA
GO:2000778positive regulation of interleukin-6 secretionIDA
cellular_component
GO:0005794Golgi apparatusTAS
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneIDA
GO:0016021integral to membraneIEA
GO:0031143pseudopodiumISS
molecular_function
GO:0001965G-protein alpha-subunit bindingISS
GO:0004871signal transducer activityIEA
GO:0004872receptor activityIEA
GO:0004930G-protein coupled receptor activityIMP
GO:0004930G-protein coupled receptor activityISS
GO:0005102receptor bindingTAS
GO:0005515protein bindingIPI
GO:0015057thrombin receptor activityIEA
GO:0031681G-protein beta-subunit bindingISS

Protein-protein interaction details for F2RL1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
UBCAffinity Capture-Westernphysical15708858