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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FGF2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2247
Official gene symbolFGF2
Full namefibroblast growth factor 2 (basic)
Aliases,BFGF,FGFB,HBGF-2,
Gene summaryThe protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q26-q27
Gene position123747863 - 123819390  Map Viewer
Gene orientationplus
Gene size71528 bp
Gene sequence
OMIM ID134920