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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FGF2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000186 activation of MAPKK activity IEA GO:0000187 activation of MAPK activity TAS GO:0000189 MAPK import into nucleus IEA GO:0001658 branching involved in ureteric bud morphogenesis IDA GO:0001759 organ induction IEA GO:0001934 positive regulation of protein phosphorylation IEA GO:0001938 positive regulation of endothelial cell proliferation IMP GO:0002042 cell migration involved in sprouting angiogenesis IDA GO:0002042 cell migration involved in sprouting angiogenesis IGI GO:0006661 phosphatidylinositol biosynthetic process IDA GO:0006700 C21-steroid hormone biosynthetic process IEA GO:0006915 apoptosis IEA GO:0006935 chemotaxis TAS GO:0007165 signal transduction IEA GO:0007243 intracellular protein kinase cascade IEA GO:0007265 Ras protein signal transduction TAS GO:0007268 synaptic transmission IEA GO:0007399 nervous system development TAS GO:0008284 positive regulation of cell proliferation IGI GO:0008285 negative regulation of cell proliferation IEA GO:0008286 insulin receptor signaling pathway TAS GO:0008543 fibroblast growth factor receptor signaling pathway IDA GO:0008543 fibroblast growth factor receptor signaling pathway IGI GO:0008543 fibroblast growth factor receptor signaling pathway IPI GO:0008543 fibroblast growth factor receptor signaling pathway TAS GO:0009887 organ morphogenesis TAS GO:0010001 glial cell differentiation IEA GO:0010863 positive regulation of phospholipase C activity IDA GO:0017158 regulation of calcium ion-dependent exocytosis IEA GO:0021762 substantia nigra development IEA GO:0021940 positive regulation of cerebellar granule cell precursor proliferation IEA GO:0030308 negative regulation of cell growth IEA GO:0030324 lung development IEA GO:0032958 inositol phosphate biosynthetic process IDA GO:0042060 wound healing TAS GO:0042660 positive regulation of cell fate specification IDA GO:0043536 positive regulation of blood vessel endothelial cell migration IDA GO:0043537 negative regulation of blood vessel endothelial cell migration IDA GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IDA GO:0045669 positive regulation of osteoblast differentiation IEA GO:0045765 regulation of angiogenesis TAS GO:0045766 positive regulation of angiogenesis IDA GO:0045892 negative regulation of transcription, DNA-dependent IEA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IDA GO:0046668 regulation of retinal cell programmed cell death IEA GO:0048598 embryonic morphogenesis TAS GO:0048678 response to axon injury IEA GO:0048864 stem cell development IEA GO:0050918 positive chemotaxis IDA GO:0051209 release of sequestered calcium ion into cytosol IDA GO:0051726 regulation of cell cycle IEA GO:0051781 positive regulation of cell division IEA GO:0060045 positive regulation of cardiac muscle cell proliferation IDA GO:0060128 corticotropin hormone secreting cell differentiation IEA GO:0060129 thyroid-stimulating hormone-secreting cell differentiation IEA GO:0060548 negative regulation of cell death IDA GO:0060591 chondroblast differentiation IDA GO:0060644 mammary gland epithelial cell differentiation IEA GO:0070374 positive regulation of ERK1 and ERK2 cascade IDA cellular_component GO:0005576 extracellular region TAS GO:0005615 extracellular space IEA GO:0005634 nucleus IEA GO:0005737 cytoplasm IEA molecular_function GO:0004713 protein tyrosine kinase activity TAS GO:0005104 fibroblast growth factor receptor binding IPI GO:0005125 cytokine activity IDA GO:0005245 voltage-gated calcium channel activity IEA GO:0005515 protein binding IPI GO:0008083 growth factor activity IDA GO:0008201 heparin binding IEA GO:0017134 fibroblast growth factor binding IEA GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity IDA GO:0042056 chemoattractant activity IDA

Protein-protein interaction details for FGF2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SDC1 Co-purification physical 16982797 SDC2 Co-purification physical 16982797 SDC4 Co-purification physical 16982797 CSNK2A1 Reconstituted Complex physical 12145206 CSNK2A2 Reconstituted Complex physical 12145206 CSNK2B Reconstituted Complex physical 12145206 CSNK2A1 Biochemical Activity physical 12145206 GPC3 Affinity Capture-Western physical 12478660 RPS19 Co-purification physical 11716516 RPS19 Reconstituted Complex physical 11716516 VTN Reconstituted Complex physical 11796824 FGFBP1 Reconstituted Complex physical 11509569 SDC3 Reconstituted Complex physical 8344959 FGFR1 Reconstituted Complex physical 10950949 GPC4 Reconstituted Complex physical 11066092 RPL6 Two-hybrid physical 9826564 RPL6 Reconstituted Complex physical 9826564