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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NLRP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID22861
Official gene symbolNLRP1
Full nameNLR family, pyrin domain containing 1
Aliases,CARD7,CLR17.1,DEFCAP,DEFCAP-L/S,DKFZp586O1822,KIAA0926,NAC,NALP1,PP1044,SLEV1,VAMAS1,
Gene summaryThis gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq]
LocationChromosome: 17   Locus: 17p13.2
Gene position5487832 - 5404719  Map Viewer
Gene orientationminus
Gene size83114 bp
Gene sequence
OMIM ID606636