GO/PPI information

Database of mammalian genes

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Gene

Protein

Transcript

Promoter

Expression

GO/PPI

PubMed

Cross reference

Gene Ontology information for NLRP1 (Homo sapiens) (Information is obtained from AmiGO)

ID	Term	Evidence
biological_process
GO:0002218	activation of innate immune response	TAS
GO:0006917	induction of apoptosis	IDA
GO:0006917	induction of apoptosis	NAS
GO:0006919	activation of caspase activity	IDA
GO:0006919	activation of caspase activity	NAS
GO:0006952	defense response	IEA
GO:0032495	response to muramyl dipeptide	ISS
GO:0042742	defense response to bacterium	ISS
GO:0042981	regulation of apoptosis	IEA
GO:0045087	innate immune response	TAS
GO:0050718	positive regulation of interleukin-1 beta secretion	ISS
GO:0050727	regulation of inflammatory response	IC
GO:0051402	neuron apoptosis	IDA
cellular_component
GO:0005622	intracellular	IC
GO:0005634	nucleus	IDA
GO:0005737	cytoplasm	IEA
GO:0005829	cytosol	TAS
GO:0072558	NALP1 inflammasome complex	TAS
molecular_function
GO:0000166	nucleotide binding	IEA
GO:0005515	protein binding	IPI
GO:0005524	ATP binding	IDA
GO:0005524	ATP binding	IEA
GO:0008656	caspase activator activity	NAS
GO:0019899	enzyme binding	IPI
GO:0019904	protein domain specific binding	IPI

Protein-protein interaction details for NLRP1 (Homo sapiens) (Information is obtained from BioGRID)