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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TAB2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23118
Official gene symbolTAB2
Full nameTGF-beta activated kinase 1/MAP3K7 binding protein 2
Aliases,FLJ21885,KIAA0733,MAP3K7IP2,
Gene summaryThe protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q25.1-q25.3
Gene position149639436 - 149732747  Map Viewer
Gene orientationplus
Gene size93312 bp
Gene sequence
OMIM ID605101