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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TAB2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000187 activation of MAPK activity TAS GO:0002218 activation of innate immune response TAS GO:0002224 toll-like receptor signaling pathway TAS GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS GO:0007249 I-kappaB kinase/NF-kappaB cascade TAS GO:0007254 JNK cascade TAS GO:0007507 heart development IMP GO:0008063 Toll signaling pathway TAS GO:0034130 toll-like receptor 1 signaling pathway TAS GO:0034134 toll-like receptor 2 signaling pathway TAS GO:0034138 toll-like receptor 3 signaling pathway TAS GO:0034142 toll-like receptor 4 signaling pathway TAS GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IEP GO:0045087 innate immune response TAS GO:0045860 positive regulation of protein kinase activity IDA GO:0050852 T cell receptor signaling pathway TAS GO:0051092 positive regulation of NF-kappaB transcription factor activity TAS GO:0051403 stress-activated MAPK cascade TAS GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway TAS cellular_component GO:0005622 intracellular IEA GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS GO:0005886 plasma membrane TAS GO:0010008 endosome membrane TAS molecular_function GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0016301 kinase activity IEA GO:0046872 metal ion binding IEA GO:0070530 K63-linked polyubiquitin binding IDA

Protein-protein interaction details for TAB2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CS Affinity Capture-MS physical 14743216 TAB1 Affinity Capture-MS physical 14743216 MAP3K7 Affinity Capture-Western physical 14670075 TAB1 Affinity Capture-Western physical 14670075 MAP3K7 Affinity Capture-Western physical 14670075 TAB1 Affinity Capture-Western physical 14670075 TAB3 Affinity Capture-Western physical 14633987 TAB3 Affinity Capture-Western physical 14633987 TAB2 Affinity Capture-Western physical 14633987 TRAF6 Affinity Capture-Western physical 14633987 NCOR1 Two-hybrid physical 12150997 NCOR1 Affinity Capture-Western physical 12150997 HDAC3 Reconstituted Complex physical 12150997 HDAC1 Reconstituted Complex physical 12150997 HDAC5 Reconstituted Complex physical 12150997 TBL1X Reconstituted Complex physical 12150997 HDAC3 Affinity Capture-Western physical 12150997 NCOR1 Affinity Capture-Western physical 12150997 NCOR1 Reconstituted Complex physical 12150997 NFKB1 Reconstituted Complex physical 12150997 NFKB1 Affinity Capture-Western physical 12150997 TNFRSF11A Affinity Capture-Western physical 11809792 XIAP Affinity Capture-Western physical 12048196 TRAF6 Affinity Capture-Western physical 10882101 TRAF2 Affinity Capture-Western physical 10882101 TRAF6 Affinity Capture-Western physical 10882101 TAB1 Affinity Capture-Western physical 10882101 MAP3K7 Affinity Capture-Western physical 10882101 TRAF6 Two-hybrid physical 11259596 TAB2 Two-hybrid physical 11259596 TRAF6 Affinity Capture-Western physical 11259596 MAP3K7 Two-hybrid physical 11259596 TRAF2 Affinity Capture-Western physical 19150425 TRAF6 Affinity Capture-Western physical 19112497 NUMBL Two-hybrid physical 18299187 NUMBL Reconstituted Complex physical 18299187 NUMBL Affinity Capture-Western physical 18299187 NUMBL Affinity Capture-Western physical 18299187 TRAF6 Affinity Capture-Western physical 18299187 RIPK1 Affinity Capture-Western physical 18299187 TRAF6 Affinity Capture-Western physical 18180283 IRAK1 Affinity Capture-Western physical 18180283 CNTN2 Affinity Capture-Western physical 17986383 MAP3K7 Affinity Capture-Western physical 14633987 TRAF2 Affinity Capture-Western physical 14633987 UBC Affinity Capture-Western physical 14633987 MAP3K7 Affinity Capture-Western physical 14633987 TNF Affinity Capture-MS physical 20005846 UBC Reconstituted Complex physical 19935683 UBC Co-crystal Structure physical 19935683 TNF Affinity Capture-Western physical 16603398 MAP3K7 Affinity Capture-Western physical 16603398 RIPK1 Affinity Capture-Western physical 16603398 RIPK2 Affinity Capture-Western physical 18079694 PPP6C Affinity Capture-Western physical 19955178 MAP3K7 Affinity Capture-Western physical 19955178 UBC Affinity Capture-Western physical 19675569 IRAK1 Affinity Capture-Western physical 19675569 TRAF6 Affinity Capture-Western physical 19675569 TRAF3IP1 Two-hybrid physical 17043677 MAP3K7 Affinity Capture-Western physical 19026643 TIRAP Affinity Capture-MS physical 21903422 TAB1 Affinity Capture-MS physical 21903422 TAB1 Affinity Capture-MS physical 21903422 TAB3 Affinity Capture-MS physical 21903422 MAP3K7 Affinity Capture-MS physical 21903422 TAB3 Affinity Capture-MS physical 21903422 MAP3K7 Affinity Capture-MS physical 21903422 UBC Affinity Capture-MS physical 21987572