Entrez gene ID | | 2521 |
Official gene symbol | | FUS |
Full name | | fused in sarcoma |
Aliases | | ,ALS6,FUS1,HNRNPP2,POMP75,TLS, |
Gene summary | | This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16p11.2 |
Gene position | | 31191431 - 31206192 Map Viewer |
Gene orientation | | plus |
Gene size | | 14762 bp |
Gene sequence |
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OMIM ID | | 137070 |
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