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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for FUS (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000398 nuclear mRNA splicing, via spliceosome TAS GO:0008219 cell death IEA GO:0008380 RNA splicing TAS GO:0010467 gene expression TAS cellular_component GO:0005622 intracellular IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005730 nucleolus IDA GO:0005737 cytoplasm IEA molecular_function GO:0000166 nucleotide binding IEA GO:0003676 nucleic acid binding IEA GO:0003677 DNA binding IEA GO:0003723 RNA binding IEA GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for FUS (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID EIF6 Affinity Capture-MS physical 17353931 USF2 Affinity Capture-MS physical 17353931 PRMT1 Biochemical Activity physical 12183049 PRMT1 Biochemical Activity physical 11850402 PTBP2 Affinity Capture-Western physical 12581738 SRRM1 Affinity Capture-Western physical 12581738 PRMT1 Two-hybrid physical 16169070 SPI1 Co-purification physical 9478924 SPI1 Affinity Capture-Western physical 9478924 SPI1 Affinity Capture-Western physical 9478924 SPI1 Reconstituted Complex physical 9478924 YBX1 Affinity Capture-Western physical 12168660 ILF3 Two-hybrid physical 11438536 ILF3 Affinity Capture-Western physical 11438536 ILF3 Affinity Capture-Western physical 11438536 SF1 Reconstituted Complex physical 9660765 SRSF10 Affinity Capture-Western physical 10779324 SRSF10 Two-hybrid physical 10779324 THRA Reconstituted Complex physical 9440806 RXRA Reconstituted Complex physical 9440806 RELA Affinity Capture-Western physical 11278855 RELA Reconstituted Complex physical 11278855 OTUB1 Affinity Capture-Western physical 18954305 ZMYM2 Affinity Capture-MS physical 15975576 SARNP Affinity Capture-Western physical 17196963 WBP4 Affinity Capture-MS physical 16055720 TARDBP Affinity Capture-Western physical 20720006 TARDBP Reconstituted Complex physical 20720006 DGCR8 Affinity Capture-MS physical 17765891 UBC Affinity Capture-MS physical 22178446 PCM1 Affinity Capture-MS physical 21956701