| Entrez gene ID | | 2898 |
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| Official gene symbol | | GRIK2 |
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| Full name | | glutamate receptor, ionotropic, kainate 2 |
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| Aliases | | ,EAA4,GLR6,GLUK6,GLUR6,MGC74427,MRT6, |
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| Gene summary | | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq] |
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| Location | | Chromosome: 6 Locus: 6q16.3-q21 |
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| Gene position | | 101846861 - 102517958 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 671098 bp |
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| Gene sequence |
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| OMIM ID | | 138244 |
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