Entrez gene ID | | 2899 |
Official gene symbol | | GRIK3 |
Full name | | glutamate receptor, ionotropic, kainate 3 |
Aliases | | ,EAA5,GLR7,GLUR7,GluR7a, |
Gene summary | | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p34-p33 |
Gene position | | 37499844 - 37261128 Map Viewer |
Gene orientation | | minus |
Gene size | | 238717 bp |
Gene sequence |
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OMIM ID | | 138243 |
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